| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2243 |
Name | FGA |
Synonym | Fib2;fibrinogen alpha chain;FGA;fibrinogen alpha chain |
Definition | fibrinogen, A alpha polypeptide |
Position | 4q28 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Common Pathway;PID Reactome;500303 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | intrinsic prothrombin activation pathway;PID BioCarta;100122 |
Pathway | extrinsic prothrombin activation pathway;PID BioCarta;100168 |
Pathway | Complement and coagulation cascades;KEGG PATHWAY;hsa04610 |
Pathway | fibrinolysis pathway;PID BioCarta;100164 |
Pathway | Blood coagulation;PANTHER;P00011 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Pathway | Plasminogen activating cascade;PANTHER;P00050 |
Disease | Hematologic diseases;KEGG DISEASE |
Disease | HEMATOLOGICAL;GAD |
Disease | plasma fibrinogen levels in smokers and non-smokers;GAD |
Disease | Afibrinogenemia, congenital;OMIM |
Disease | Afibrinogenemia;KEGG DISEASE;H00222 |
Disease | Obesity;FunDO |
Disease | Circulatory system diseases;KEGG DISEASE |
Disease | fibrinogen myocardial infarct;GAD |
Disease | METABOLIC;GAD |
Disease | post-trauma fibrinogen increase;GAD |
Disease | Inherited thrombophilia;KEGG DISEASE;H00223 |
Disease | Dysfibrinogenemia, alpha type, causing bleeding diathesis;OMIM |
Disease | CARDIOVASCULAR;GAD |
Disease | renal amyloidosis;GAD |
Disease | Cerebrovascular disorder;FunDO |
Disease | Hemorrhagic disorder;FunDO |
Disease | angina;GAD |
Disease | Amyloidosis, hereditary renal;OMIM |
Disease | Amyloidosis;FunDO |
Disease | Dysfibrinogenemia, alpha type, causing recurrent thrombosis;OMIM |
Disease | thromboembolism, venous;GAD |
Disease | fibrinogen;GAD |
External Links | |
Links to Entrez Gene | 2243 |
Links to all GeneRIF Items | 2243 |
Links to iHOP | 2243 |
Sequence Information | |
Nucleotide Sequence | >2243 : length: 3655 AGCAATCCTTTCTTTCAGCTGGAGTGCTCCTCAGGAGCCAGCCCCACCCTTAGAAAAGAT GTTTTCCATGAGGATCGTCTGCCTGGTCCTAAGTGTGGTGGGCACAGCATGGACTGCAGA TAGTGGTGAAGGTGACTTTCTAGCTGAAGGAGGAGGCGTGCGTGGCCCAAGGGTTGTGGA AAGACATCAATCTGCCTGCAAAGATTCAGACTGGCCCTTCTGCTCTGATGAAGACTGGAA CTACAAATGCCCTTCTGGCTGCAGGATGAAAGGGTTGATTGATGAAGTCAATCAAGATTT TACAAACAGAATAAATAAGCTCAAAAATTCACTATTTGAATATCAGAAGAACAATAAGGA TTCTCATTCGTTGACCACTAATATAATGGAAATTTTGAGAGGCGATTTTTCCTCAGCCAA TAACCGTGATAATACCTACAACCGAGTGTCAGAGGATCTGAGAAGCAGAATTGAAGTCCT GAAGCGCAAAGTCATAGAAAAAGTACAGCATATCCAGCTTCTGCAGAAAAATGTTAGAGC TCAGTTGGTTGATATGAAACGACTGGAGGTGGACATTGATATTAAGATCCGATCTTGTCG AGGGTCATGCAGTAGGGCTTTAGCTCGTGAAGTAGATCTGAAGGACTATGAAGATCAGCA GAAGCAACTTGAACAGGTCATTGCCAAAGACTTACTTCCCTCTAGAGATAGGCAACACTT ACCACTGATAAAAATGAAACCAGTTCCAGACTTGGTTCCCGGAAATTTTAAGAGCCAGCT TCAGAAGGTACCCCCAGAGTGGAAGGCATTAACAGACATGCCGCAGATGAGAATGGAGTT AGAGAGACCTGGTGGAAATGAGATTACTCGAGGAGGCTCCACCTCTTATGGAACCGGATC AGAGACGGAAAGCCCCAGGAACCCTAGCAGTGCTGGAAGCTGGAACTCTGGGAGCTCTGG ACCTGGAAGTACTGGAAACCGAAACCCTGGGAGCTCTGGGACTGGAGGGACTGCAACCTG GAAACCTGGGAGCTCTGGACCTGGAAGTACTGGAAGCTGGAACTCTGGGAGCTCTGGAAC TGGAAGTACTGGAAACCAAAACCCTGGGAGCCCTAGACCTGGTAGTACCGGAACCTGGAA TCCTGGCAGCTCTGAACGCGGAAGTGCTGGGCACTGGACCTCTGAGAGCTCTGTATCTGG TAGTACTGGACAATGGCACTCTGAATCTGGAAGTTTTAGGCCAGATAGCCCAGGCTCTGG GAACGCGAGGCCTAACAACCCAGACTGGGGCACATTTGAAGAGGTGTCAGGAAATGTAAG TCCAGGGACAAGGAGAGAGTACCACACAGAAAAACTGGTCACTTCTAAAGGAGATAAAGA GCTCAGGACTGGTAAAGAGAAGGTCACCTCTGGTAGCACAACCACCACGCGTCGTTCATG CTCTAAAACCGTTACTAAGACTGTTATTGGTCCTGATGGTCACAAAGAAGTTACCAAAGA AGTGGTGACCTCCGAAGATGGTTCTGACTGTCCCGAGGCAATGGATTTAGGCACATTGTC TGGCATAGGTACTCTGGATGGGTTCCGCCATAGGCACCCTGATGAAGCTGCCTTCTTCGA CACTGCCTCAACTGGAAAAACATTCCCAGGTTTCTTCTCACCTATGTTAGGAGAGTTTGT CAGTGAGACTGAGTCTAGGGGCTCAGAATCTGGCATCTTCACAAATACAAAGGAATCCAG TTCTCATCACCCTGGGATAGCTGAATTCCCTTCCCGTGGTAAATCTTCAAGTTACAGCAA ACAATTTACTAGTAGCACGAGTTACAACAGAGGAGACTCCACATTTGAAAGCAAGAGCTA TAAAATGGCAGATGAGGCCGGAAGTGAAGCCGATCATGAAGGAACACATAGCACCAAGAG AGGCCATGCTAAATCTCGCCCTGTCAGAGACTGTGATGATGTCCTCCAAACACATCCTTC AGGTACCCAAAGTGGCATTTTCAATATCAAGCTACCGGGATCCAGTAAGATTTTTTCTGT TTATTGCGATCAAGAGACCAGTTTGGGAGGATGGCTTTTGATCCAGCAAAGAATGGATGG ATCACTGAATTTTAACCGGACCTGGCAAGACTACAAGAGAGGTTTCGGCAGCCTGAATGA CGAGGGGGAAGGAGAATTCTGGCTAGGCAATGACTACCTCCACTTACTAACCCAAAGGGG CTCTGTTCTTAGGGTTGAATTAGAGGACTGGGCTGGGAATGAAGCTTATGCAGAATATCA CTTCCGGGTAGGCTCTGAGGCTGAAGGCTATGCCCTCCAAGTCTCCTCCTATGAAGGCAC TGCGGGTGATGCTCTGATTGAGGGTTCCGTAGAGGAAGGGGCAGAGTACACCTCTCACAA CAACATGCAGTTCAGCACCTTTGACAGGGATGCAGACCAGTGGGAAGAGAACTGTGCAGA AGTCTATGGGGGAGGCTGGTGGTATAATAACTGCCAAGCAGCCAATCTCAATGGAATCTA CTACCCTGGGGGCTCCTATGACCCAAGGAATAACAGTCCTTATGAGATTGAGAATGGAGT GGTCTGGGTTTCCTTTAGAGGGGCAGATTATTCCCTCAGGGCTGTTCGCATGAAAATTAG GCCCCTTGTGACCCAATAGGCTGAAGAAGTGGGAATGGGAGCACTCTGTCTTCTTTGCTA GAGAAGTGGAGAGAAAATACAAAAGGTAAAGCAGTTGAGATTCTCTACAACCTAAAAAAT TCCTAGGTGCTATTTTCTTATCCTTTGTACTGTAGCTAAATGTACCTGAGACATATTAGT CTTTGAAAAATAAAGTTATGTAAGGTTTTTTTTATCTTTAAATAGCTCTGTGGGTTTTAA CATTTTTATAAAGATATACCAAGGGCCATTCAGTACATCAGGAAAGTGGCAGACAGAAGC TTCTCTCTGCAACCTTGAAGACTATTGGTTTGAGAACTTCTCTTCCCATACCACCCAAAA TCATAATGCCATTGGAAAGCAAAAAGTTGTTTTATCCATTTGATTTGAATTGTTTTAAGC CAATATTTTAAGGTAAAACTCACTGAATCTAACCATAGCTGACCTTTGTAGTAGAATTTA CAACTTATAATTACAATGCACAATTTATAATTACAATATGTATTTATGTCTTTTGCTATG GAGCAAATCCAGGAAGGCAAGAGAAACATTCTTTCCTAAATATAAATGAAAATCTATCCT TTAAACTCTTCCACTAGACGTTGTAATGCACACTTATTTTTTTCCCAAGGAGTAACCAAT TTCTTTCTAAAACACATTTAAAATTTTAAAACTATTTATGAATATTAAAAAAAGACATAA TTCACACATTAATAAACAATCTCCCAAGTATTGATTTAACTTCATTTTTCTAATAATCAT AAACTATATTCTGTGACATGCTAATTATTATTAAATGTAAGTCGTTAGTTCGAAAGCCTC TCACTAAGTATGATCTATGCTATATTCAAAATTCAACCCATTTACTTTGGTCAATATTTG ATCTAAGTTGCATCTTTAATCCTGGTGGTCTTGCCTTCTGATTTTTAATTTGTATCCTTT TCTATTAAGATATATTTGTCATTTTCTCTTGAATATGTATTAAAATATCCCAAGC |
Protein Sequence | >2243 : length: 866 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFS VYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQR GSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSH NNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG VVWVSFRGADYSLRAVRMKIRPLVTQ |