| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2067 |
Name | ERCC1 |
Synonym | COFS4|RAD10|UV20;excision repair cross-complementation group 1;ERCC1;excision repair cross-complementation group 1 |
Definition | DNA excision repair protein ERCC-1|excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) |
Position | 19q13.32 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Formation of incision complex in GG-NER;PID Reactome;500060 |
Pathway | Dual incision reaction in GG-NER;PID Reactome;500061 |
Pathway | DNA Repair;Reactome;REACT:216 |
Pathway | Formation of transcription-coupled NER (TC-NER) repair complex;PID Reactome;500065 |
Pathway | Nucleotide excision repair;KEGG PATHWAY;hsa03420 |
Pathway | Global Genomic NER (GG-NER);PID Reactome;500058 |
Disease | chromosomal damage;GAD |
Disease | Hemolytic anemia;FunDO |
Disease | Genetic disorders;KEGG DISEASE |
Disease | Prostate cancer;FunDO |
Disease | Inherited disorders of DNA repair systems;KEGG DISEASE |
Disease | gastrointestinal toxicity;GAD |
Disease | Ovarian disease;FunDO |
Disease | Azoospermia;FunDO |
Disease | lung cancer;GAD |
Disease | CANCER;GAD |
Disease | Cancer;FunDO |
Disease | Testicular tumor;FunDO |
Disease | ovarian cancer;GAD |
Disease | Neoplasms;GAD |
Disease | PHARMACOGENOMIC;GAD |
Disease | Disorders of nucleotide excision repair;KEGG DISEASE;H00403 |
Disease | Cerebrooculofacioskeletal syndrome 4;OMIM |
External Links | |
Links to Entrez Gene | 2067 |
Links to all GeneRIF Items | 2067 |
Links to iHOP | 2067 |
Sequence Information | |
Nucleotide Sequence | >2067 : length: 3400 CCGGAAGTGCTGCGAGCCCTGGGCCACGCTGGCCGTGCTGGCAGTGGGCCGCCTCGATCC CTCTGCAGTCTTTCCCTTGAGGCTCCAAGACCAGCAGGTGAGGCCTCGCGGCGCTGAAAC CGTGAGGCCCGGACCACAGGCTCCAGATGGACCCTGGGAAGGACAAAGAGGGGGTGCCCC AGCCCTCAGGGCCGCCAGCAAGGAAGAAATTTGTGATACCCCTCGACGAGGATGAGGTCC CTCCTGGAGTGGCCAAGCCCTTATTCCGATCTACACAGAGCCTTCCCACTGTGGACACCT CGGCCCAGGCGGCCCCTCAGACCTACGCCGAATATGCCATCTCACAGCCTCTGGAAGGGG CTGGGGCCACGTGCCCCACAGGGTCAGAGCCCCTGGCAGGAGAGACGCCCAACCAGGCCC TGAAACCCGGGGCAAAATCCAACAGCATCATTGTGAGCCCTCGGCAGAGGGGCAATCCCG TACTGAAGTTCGTGCGCAATGTGCCCTGGGAATTTGGCGACGTAATTCCCGACTATGTGC TGGGCCAGAGCACCTGTGCCCTGTTCCTCAGCCTCCGCTACCACAACCTGCACCCAGACT ACATCCATGGGCGGCTGCAGAGCCTGGGGAAGAACTTCGCCTTGCGGGTCCTGCTTGTCC AGGTGGATGTGAAAGATCCCCAGCAGGCCCTCAAGGAGCTGGCTAAGATGTGTATCCTGG CCGACTGCACATTGATCCTCGCCTGGAGCCCCGAGGAAGCTGGGCGGTACCTGGAGACCT ACAAGGCCTATGAGCAGAAACCAGCGGACCTCCTGATGGAGAAGCTAGAGCAGGACTTCG TCTCCCGGGTGACTGAATGTCTGACCACCGTGAAGTCAGTCAACAAAACGGACAGTCAGA CCCTCCTGACCACATTTGGATCTCTGGAACAGCTCATCGCCGCATCAAGAGAAGATCTGG CCTTATGCCCAGGCCTGGGCCCTCAGAAAGCCCGGAGGCTGTTTGATGTCCTGCACGAGC CCTTCTTGAAAGTACCCTGATGACCCCAGCTGCCAAGGAAACCCCCAGTGTAATAATAAA TCGTCCTCCCAGGCCAGGCTCCTGCTGGCTGCGCTGGTGCAGTCTCTGGGGAGGGATTCT GGGGGTGTCACCTTCTGGTGGCCCAGGTGGGCACCTTCAGCTTTCTTTAGTTCCTCAGTT TCCCGGGGGCAGACTACACAGGCTGCTGCTGCTGCTGCTTCCGCTTCTTGTCCCGGCCTG TGGGAGCCTCCTCCCCAGACTCTGAATTCAGTGGCGGCCCTGGCATCTCCTCTTGGGGCA CTGTCTCTGGCATCCGGCTTTCCTGACTCTGCTTCTTCCTCTTCTTGGTGGATCCCGGAG TTGCCCTGGCTTCAGGCTGTCCCTCCCCTGGCAGTTCAGGCTCTAGTGGCTGAATTGGCT CAGTCACTGTGTGACCTCTCTCTTTCTTCTTCTTCTTCTTCTTGGTGGATGTGGGAGCTG CCTGAGGCTCAAGGTCATCCGGCAGCTCAGGCCCCACCACCTCTGTCTCTGGCTCCACTG TGGCATCTTGCTGTTTTTCTTTCTTCGTCTTCTTTTTGGGAGCTGCCAGAGCTGCCTGGG CCTGAGGCTTCGCTCCTTCTGGCTGTTGAGGCGCCATGGTCCCCCCTGGGGACTCCAGAG GCTTCATCTCCGGCTCCACTGGCTCCATCGCCTCCGTCCCTGGCTCCATCATTGCCATCT GTCCCTTTTCTTTTTTCCTCTTCTTCGTAGGGGGCAGAGGGATGGCTTCCTCCAGTGGCT CCACCTTCACCTGTGGCTGAGACTCAACTGTCACCCCCTCCTCTGGCTCCATCCCTTCCG TCCCCTTTTGCCTCTTTCTCTTTTTGGTCGGGGACAGGACTGTGTCTTCTAGAGGCTCAG TGTTAATCTGTTCCTGCTTCACTGTCTTGTCTTCTGGCTCGAAGGTTTCTTTCCCTTTGG GCTTCTTCCTCTTCTTGGTGGTGGACGGGAACAGCACTCCCAGAGGCTCCAGTGTCTCCA CTGTGGGCTCTGTCCCCACAGGCCCTGCTGCCTCTGGTTCTTTCAGCTGCTGATTTTTTT TCTTCTTCTTCTTCCGCACATCCATTTCTGGCGACCCCAAAGCCATGTCCACCTCCAGGG CCCCGTGCCCATTCACTGCCTCCTGAGTGACTGGGGCCTCTGTCACCTGCATCTCCTTTT TCTTCTTCCCTGAGGTGAGCAGGTTGGGGGCCAAGGCTGACCTAGGCCCTGTGACTGGTG GGTTGCCCCCAAAGGCACAGAACCGAGGCCTCAGGCCAGGAGGGATCTGTGGTGGGGGAC TTGCTGGGATGGGCTGCAGAGGGCTCCCTGACAGGGATTGCTGGGGACCCTCAAGGATCC TTAGGGTGCCCTGGGGGGCTGAGGCACAGGTGAGTCCACCTCCTGCCTCCGTTGAGGGGG CCAGCAGGGTCGCTTCTCCAGCTTGGGGACAGCTGCTGAGGACTCGATAGCGGTGCCGCT TGCCTGCCAATTTGCCCTTGACGATCTGGGAGCCAGAGAGAGGCACATGCCGCCCATTGA AGCTACAGAGAGAAACAGGGAGGGCAGAGGCTTAAGTGGAACAGGAGAGGGAAGGTTTTT TGATTTTTTTTTTGTTTTTTTTTGAGAGAGTCTTGCTCTGTTGCCTAGGCTGGAGTGCAG TGGCATGATCTCGGCTCACTGCAATGTCCACCTCCTGGGTTCAAGCGATTCTCCTGCCTC AGCCTCTCAAGTAGCTGGGATTACAGGCACCTGCCACCACGCCCAGCCAATTTTTGTATT TTTAGTAGAGACAATTTCACTATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTG ATCTGCTCGCCTCGGCCTCCCAAAGGATGGGATTACAGGCACCAGCCACTGCGCCTGGCT GGCCTCTGGTTTTTAATAAAACATGACTAGAGTGACTCCATCTTAAAGTGAGTAGCTAGG CACTTACAAGGTTCATGCTTATGGCCTGAAAATAACCACATCCCAGGCTGACCACCAATT ATAATTACAGAATATTTATGGCCATACAGAACATGTTCCACCAAGCCTGCAGAATGTCCA AATGTCCTAAGAATGCAGCCCCCATTACTTAAATATAACATAAATGAGCAAGCTTAGGTT GCAGGATTAATGGTCGTGGATAACACCAATAGCCCCTACCTTTAGTGAGCTTATCTGCAC ACTCCAAGTTTAACTATAGTTCCTTATAGTTTCTTATAAGTAGAAATACTAACAAAGGGC TGTGGGTTTCTCCCCCTGCTTTCTGAGGACACTCTACTCTGTAAAGGAGTAGTTTCCAAT AAACTTGTTTCTTTCACTGTGCAAAAAAAAAAAAAAAAAA |
Protein Sequence | >2067 : length: 323 MDPGKDKEGVPQPSGPPARKKFVIPLDEDEVPPGVAKPLFRSTQSLPTVDTSAQAAPQTY AEYAISQPLEGAGATCPTGSEPLAGETPNQALKPGAKSNSIIVSPRQRGNPVLKFVRNVP WEFGDVIPDYVLGQSTCALFLSLRYHNLHPDYIHGRLQSLGKNFALRVLLVQVDVKDPQQ ALKELAKMCILADCTLILAWSPEEAGRYLETYKAYEQKPADLLMEKLEQDFVSRVTECLT TVKSVNKTDSQTLLTTFGSLEQLIAASREDLALCPGLGPQKVRALGKNPRSWGKERAPNK HNLRPQSFKVKKEPKTRHSGFRL |