| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2047 |
Name | EPHB1 |
Synonym | ELK|EPHT2|Hek6|NET;EPH receptor B1;EPHB1;EPH receptor B1 |
Definition | EK6|EPH-like kinase 6|eph tyrosine kinase 2|ephrin type-B receptor 1|neuronally-expressed EPH-related tyrosine kinase|soluble EPHB1 variant 1|tyrosine-protein kinase receptor EPH-2 |
Position | 3q21-q23 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Ephrin B reverse signaling;PID Curated;200173 |
Pathway | EPHB forward signaling;PID Curated;200041 |
Pathway | EphrinB-EPHB pathway;PID Curated;200141 |
Disease | Stomach cancer;FunDO |
Disease | Neoplasm metastasis;FunDO |
External Links | |
Links to Entrez Gene | 2047 |
Links to all GeneRIF Items | 2047 |
Links to iHOP | 2047 |
Sequence Information | |
Nucleotide Sequence | >2047 : length: 4691 GTCAGTCTGGCCGGCTCCGTCCTCCCGTAGGCTCCGCTGTAGCTAGCAATGTGACACCAG GACGCACTCGCTCTCGCGCGCTCTCCCAGGCTCGTTCTCCCTCGCCCTCTCTCTCTCACA CACGCACGCACACACCCACCTCTCCCATAAACACACACACACACATGCACACCCACACCC ACGCGCGCCCGCACCGCCCCACGCGCACACACTCCTGCCCACGCCCACGCAGCGCTCCGG GAAGTCCGGTCCGGGCGAGAGCGCGAAAGGATACCGAGAAGCCACCCGCGGAGAGCGCAG CGGCGCCCTGGGACGCGGCGCTCTCCCGGCGCTGCTGCCTCGGCTTGGTCTCGGCCTGCG GGCCGTCGGCCGGCGATGGCCCTGGATTATCTACTACTGCTCCTCCTGGCATCCGCAGTG GCTGCGATGGAAGAAACGTTAATGGACACCAGAACGGCTACTGCAGAGCTGGGCTGGACG GCCAATCCTGCGTCCGGGTGGGAAGAAGTCAGTGGCTACGATGAAAACCTGAACACCATC CGCACCTACCAGGTGTGCAATGTCTTCGAGCCCAACCAGAACAATTGGCTGCTCACCACC TTCATCAACCGGCGGGGGGCCCATCGCATCTACACAGAGATGCGCTTCACTGTGAGAGAC TGCAGCAGCCTCCCTAATGTCCCAGGATCCTGCAAGGAGACCTTCAACTTGTATTACTAT GAGACTGACTCTGTCATTGCCACCAAGAAGTCAGCCTTCTGGTCTGAGGCCCCCTACCTC AAAGTAGACACCATTGCTGCAGATGAGAGCTTCTCCCAGGTGGACTTTGGGGGAAGGCTG ATGAAGGTAAACACAGAAGTCAGGAGCTTTGGGCCTCTTACTCGGAATGGTTTTTACCTC GCTTTTCAGGATTATGGAGCCTGTATGTCTCTTCTTTCTGTCCGTGTCTTCTTCAAAAAG TGTCCCAGCATTGTGCAAAATTTTGCAGTGTTTCCAGAGACTATGACAGGGGCAGAGAGC ACATCTCTGGTGATTGCTCGGGGCACATGCATCCCCAACGCAGAGGAAGTGGACGTGCCC ATCAAACTCTACTGCAACGGGGATGGGGAATGGATGGTGCCTATTGGGCGATGCACCTGC AAGCCTGGCTATGAGCCTGAGAACAGCGTGGCATGCAAGGCTTGCCCTGCAGGGACATTC AAGGCCAGCCAGGAAGCTGAAGGCTGCTCCCACTGCCCCTCCAACAGCCGCTCCCCTGCA GAGGCGTCTCCCATCTGCACCTGTCGGACCGGTTATTACCGAGCGGACTTTGACCCTCCA GAAGTGGCATGCACTAGCGTCCCATCAGGTCCCCGCAATGTTATCTCCATCGTCAATGAG ACGTCCATCATTCTGGAGTGGCACCCTCCAAGGGAGACAGGTGGGCGGGATGATGTGACC TACAACATCATCTGCAAAAAGTGCCGGGCAGACCGCCGGAGCTGCTCCCGCTGTGACGAC AATGTGGAGTTTGTGCCCAGGCAGCTGGGCCTGACGGAGTGCCGCGTCTCCATCAGCAGC CTGTGGGCCCACACCCCCTACACCTTTGACATCCAGGCCATCAATGGAGTCTCCAGCAAG AGTCCCTTCCCCCCACAGCACGTCTCTGTCAACATCACCACAAACCAAGCCGCCCCCTCC ACCGTTCCCATCATGCACCAAGTCAGTGCCACTATGAGGAGCATCACCTTGTCATGGCCA CAGCCGGAGCAGCCCAATGGCATCATCCTGGACTATGAGATCCGGTACTATGAGAAGGAA CACAATGAGTTCAACTCCTCCATGGCCAGGAGTCAGACCAACACAGCAAGGATTGATGGG CTGCGGCCTGGCATGGTATATGTGGTACAGGTGCGTGCCCGCACTGTTGCTGGCTACGGC AAGTTCAGTGGCAAGATGTGCTTCCAGACTCTGACTGACGATGATTACAAGTCAGAGCTG AGGGAGCAGCTGCCCCTGATTGCTGGCTCGGCAGCGGCCGGGGTCGTGTTCGTTGTGTCC TTGGTGGCCATCTCTATCGTCTGTAGCAGGAAACGGGCTTATAGCAAAGAGGCTGTGTAC AGCGATAAGCTCCAGCATTACAGCACAGGCCGAGGCTCCCCAGGGATGAAGATCTACATT GACCCCTTCACTTACGAGGATCCCAACGAAGCTGTCCGGGAGTTTGCCAAGGAGATTGAT GTATCTTTTGTGAAAATTGAAGAGGTCATCGGAGCAGGGGAGTTTGGAGAAGTGTACAAG GGGCGTTTGAAACTGCCAGGCAAGAGGGAAATCTACGTGGCCATCAAGACCCTGAAGGCA GGGTACTCGGAGAAGCAGCGTCGGGACTTTCTGAGTGAGGCGAGCATCATGGGCCAGTTC GACCATCCTAACATCATTCGCCTGGAGGGTGTGGTCACCAAGAGTCGGCCTGTCATGATC ATCACAGAGTTCATGGAGAATGGTGCATTGGATTCTTTCCTCAGGCAAAATGACGGGCAG TTCACCGTGATCCAGCTTGTGGGTATGCTCAGGGGCATCGCTGCTGGCATGAAGTACCTG GCTGAGATGAATTATGTGCATCGGGACCTGGCTGCTAGGAACATTCTGGTCAACAGTAAC CTGGTGTGCAAGGTGTCCGACTTTGGCCTCTCCCGCTACCTCCAGGATGACACCTCAGAT CCCACCTACACCAGCTCCTTGGGAGGGAAGATCCCTGTGAGATGGACAGCTCCAGAGGCC ATCGCCTACCGCAAGTTCACTTCAGCCAGCGACGTTTGGAGCTATGGGATCGTCATGTGG GAAGTCATGTCATTTGGAGAGAGACCCTATTGGGATATGTCCAACCAAGATGTCATCAAT GCCATCGAGCAGGACTACCGGCTGCCCCCACCCATGGACTGTCCAGCTGCTCTACACCAG CTCATGCTGGACTGTTGGCAGAAGGACCGGAACAGCCGGCCCCGGTTTGCGGAGATTGTC AACACCCTAGATAAGATGATCCGGAACCCGGCAAGTCTCAAGACTGTGGCAACCATCACC GCCGTGCCTTCCCAGCCCCTGCTCGACCGCTCCATCCCAGACTTCACGGCCTTTACCACC GTGGATGACTGGCTCAGCGCCATCAAAATGGTCCAGTACAGGGACAGCTTCCTCACTGCT GGCTTCACCTCCCTCCAGCTGGTCACCCAGATGACATCAGAAGACCTCCTGAGAATAGGC ATCACCTTGGCAGGCCATCAGAAGAAGATCCTGAACAGCATTCATTCTATGAGGGTCCAG ATAAGTCAGTCACCAACGGCAATGGCATGAGAACTCTTGTTTCTTGGGGAAGGAGAGGAG GGAAAAGGACCAGGGTCAAGGGGGACCAGAGGTTGACCACTGTGGAATGTACTGGAGAGA CTGGCTTCTCAGCTGAGGAATGCATTTCCATCAGTGAAGAATCAACCGGACCTGTTGCTA GCAGGCAATCTCCATTTCTCAGTGACAGAAGCATGTTTGAGATGCCGTGGGAAACCAAAT ATATAATAATAAAAATATAAAAAGGTGATGTTCAACAGAAGTGAAGACAAAACAATATGC ATCAGGAGAACAAGAGTAAACCCAGCTCCCACTCTCAGTGGGCTGCAGTTGCCCAACCAC AGGAAGAAAGGGAAGGAGGTAGAGGGAAGAAACAGAAGCAGTGTTCCATTTTCTTCCTCA CCAATGACATTCTTTTCTTTTCTCCTTTCGTACTCCTCCCTGAGAGTCCCCTCCCTTCTC CCACACTCGTTTCCCTTTGCTCATGACTCCTGTAGGGAAGTTTCTTCAAACAAAACCCAG CTCCTGAGTCTCCAGATGTTGTTCTGTCAGTTGCCAAAGGACTTTGCTGACCACTGCATG GGGATCCAACCAATTCAATTAATGTCTTCATATTGAAGAAGAGATGTACCTTCAATTGAA AACCTCGTTTTTCTTTTGTTTGCATTTTCTGCAAAAAGGAAAAAGAAACCACAAATTGGG GAAAAAAAAAGAAGAAAAACCTGTTTCCGTGTGCAAAAGCACACATATGTATGTCTGTGT TATAAAATGACTGTGCTTGTTCGTAACAGATGCAAACAAGAAAGAAGAACTGGGAAGTCT TTGTCCCTAGGAAATCCAAAGGGGCTGGAATATGGTGTTGGTTTGGCTTTCTGGTTGGCC CAATCGGCCTATTGGCTCAATGGGAAGAGAGGAGAGGGAGAAAAATAAAATGAAAGGAAA AAAAAAAGTTTGCAAATTCAGACAGGAAACAGGTGAGTGGTTTGAATTGGATGCAGTGTG GGCCATCCTGGAATGATACTGACTGATTAATTATTCCTGATAACATCTCAAGAAAAGGAG AAGGAAAGTGTTTCTGGAGAATGTTCTTTCACATCACTGGAATCTGCAATTCAAGAAGTG ACAAGGGAGAATTCTTGCTTTACCTATGGACTGGCTTAAGCCGTGTGGCATCCGAGGAAT GTTTCAAATGTGTCTGTGTTTCTCTTTACATTCCTTGTTGTACCTCATTGTTCAATTCAC TTTTGTAAATTCCACCTAACATTTAATTATTTTAAATTTCTCCTTTTACCTTAATCTCCT TGCTAATTTTATCTGTCTAATTAAAAAGAGCAGAAGCATGTCTGGGTTTACGTAAAAAAA AAAAAAAAAAA |
Protein Sequence | >2047 : length: 984 MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQV CNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSV IATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDY GACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYC NGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPI CTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIIC KKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPP QHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFN SSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLP LIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTY EDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEK QRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQ LVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTS SLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQD YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ PLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAG HQKKILNSIHSMRVQISQSPTAMA |