| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1908 |
Name | EDN3 |
Synonym | ET-3|ET3|HSCR4|PPET3|WS4B;endothelin 3;EDN3;endothelin 3 |
Definition | endothelin-3|preproendothelin-3 |
Position | 20q13.2-q13.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endothelins;PID Curated;200004 |
Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Disease | hypertension;GAD |
Disease | Waardenburg syndrome, type 4B;OMIM |
Disease | CARDIOVASCULAR;GAD |
Disease | Hirschsprung disease, susceptibility to, 4;OMIM |
Disease | Melanoma;FunDO |
Disease | Central hypoventilation syndrome, congenital;OMIM |
External Links | |
Links to Entrez Gene | 1908 |
Links to all GeneRIF Items | 1908 |
Links to iHOP | 1908 |
Sequence Information | |
Nucleotide Sequence | >1908 : length: 2711 CGCTGTCCTGGGTGCGCCTCGGGCCGCTGCGCTCCTGGCCAGCTCCCCCCAGCGCCTGGG AGGCGACCCCCAGTGCGCCCGGGTTCAAAGGCCCGGCGAGGCAGTTCCAGCCCCTCTGGG GGGCGGGGAGGCGACGGGGGTGGTGCAGAAGCCAGAAAAGCCCGAGCCACAGCCGGCCAG CTCCGCGCAGGGATGGGCAGCGCGCTCTGAAAGTTTATGACCGCCGCAGCCAACTCCTGG CCGGAGCTGGAGACGCAGCGAGCGATCGGCCGGCCTCGAACCCCCACAGCTGGAGGGCGA GGCCAGCTGTACCCGGCCCCAGTGCCCTTTCGCGGCCACAAGCGGCCGTCCTCCTGGTCC GGTGCTCCGGCGCCTGATCTAGGTTCATGGAGCCGGGGCTGTGGCTCCTTTTCGGGCTCA CAGTGACCTCCGCCGCAGGATTCGTGCCTTGCTCCCAGTCTGGGGATGCTGGCAGGCGCG GCGTGTCCCAGGCCCCCACTGCAGCCAGATCTGAGGGGGACTGTGAAGAGACTGTGGCTG GCCCTGGCGAGGAGACTGTGGCTGGCCCTGGCGAGGGGACTGTGGCCCCGACAGCACTGC AGGGTCCAAGCCCTGGAAGCCCTGGGCAGGAGCAGGCGGCCGAGGGGGCCCCTGAGCACC ACCGATCCAGGCGCTGCACGTGCTTCACCTACAAGGACAAGGAGTGTGTCTACTATTGCC ACCTGGACATCATTTGGATCAACACTCCCGAACAGACGGTGCCCTATGGACTGTCCAACT ACAGAGGAAGCTTCCGGGGCAAGAGGTCTGCGGGGCCACTTCCAGGGAATCTGCAGCTCT CACATCGGCCACACTTGCGCTGCGCTTGTGTGGGGAGATATGACAAGGCCTGCCTGCACT TTTGCACCCAAACTCTGGACGTCAGCAGTAATTCAAGGACGGCAGAAAAAACAGACAAAG AAGAGGAAGGGAAGGTGAGAGGTGCCAACAGAGGCCTGTGTCAAAGGAGGTTGAAGTCAA GGACCAACAAAGCAAGCAGGCTTTAGACCTCCACCATCCAAAGCTCATGCCCGGCAGTGG ACTCGCCCTCGCTCCATCTACCTGCCCCCGCTGCCTCTTTCAGGAAGGAGCCCCTTAGGA GGACAGGCCTGCAGCATCCTGGTCTCGGGAGGCTTCTGTCATTGCTCACACACAGTTCAG ATTTCCACCTCTTTATAGACAAGAAGTGAATTTGCCTGGGGCAGAACACCCACCCAAAGA GTCCCCACTTAACAATACCCCCCCCCCACGGCAAGAATGCCCAAATCCGAATGACCCCAG TTTTCCTAATGAGTAAAATGATCCCAGATGTGCCCCAGAGCATGACGCCTGCAGCTCCGG TTTCATGCAGGAAATTGGTTTTGGAGAGTTTTGGCAAGTTGGAAAGCCACTTACTGGCTT TTGACATGACTTCTCTTGGAGAATAAGTGGACTCCAAGCTAACTCTTTGCAAATGTAAAC ACATGTCCATCTTGTAATAAATGCAAAATGCCCGTGCAGCAGAAGCATGCGACTTTCATA TCCTTGCCTAGAATAGGCTGCATGGTGTATGTCAGTGAGGGCCACGAGGCGTCGGCTTTA GACACAGATCATAGCTCTACAGGAGTTTATGAATTTGAAGCTTATGGGATTTTGGCAGAG AAATTTTCAGCTGTGCTTGATACCCACCAAAAGAATGTATCTCGAAAGAATGAAGGAAGA AGAAAAAAGGATCCTTGATGTTTGTGACAAGAAAATGAGAAAGTTAGTATCTGCAATACA GAGCTTGTTCCTGTTCAGTGACTGACCCTCTGTATTCTGTATAGACACCAGGCCGATACA CAGTGGAGTTCCCAGGCCTTGTTTGCAGGAAGCCGACTGTAAAGACAGCCCCAGCTCAAG GCTATTAGGTTGAATATTTGCTTTCATGAGTAAATGTGGATCTTTGGGGAATGGCTTCAA AATAAGTCACGAACACAAATTCTTTGTAAATTATGTAAATTCCTGTTTATATAAATTGGC AACAACTTATACCGTCTGACAGTTCAAAATCTCTTTCAGCTGCGCTCTTCCCACCGAGCC GAGCTTACTGTGAGTGTGGAGATGTTATCCCACCATGTAAAGTCGCCTGCGCAGGGGAGG GCTGCCCATCTCCCCAACCCAGTCACAGAGAGATAGGAAACGGCATTTGAGTGGGTGTCC AGGGCCCCGTAGAGAGACATTTAAGATGGTGTATGACAGAGCATTGGCCTTGACCAAATG TTAAATCCTCTGTGTGTATTTCATAAGTTATTACAGGTATAAAAGTGATGACCTATCATG AGGAAATGAAAGTGGCTGATTTGCTGGTAGGATTTTGTACAGTTTAGAGAAGCGATTATT TATTGTGAAACTGTTCTCCACTCCAACTCCTTTATGTGGATCTGTTCAAAGTAGTCACTG TATATACGTATAGAGAGGTAGATAGGTAGGTAGATTTTAAATTGCATTCTGAATACAAAC TCATACTCCTTAGAGCTTGAATTACATTTTTAAAATGCATATGTGCTGTTTGGCACCGTG GCAAGATGGTATCAGAGAGAAACCCATCAATTGCTCAAATACTCAGAAAGTACTGTCAAA AGCCTAATAAAAAACCTAAAGTTTGCTCTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAA |
Protein Sequence | >1908 : length: 251 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS SNSRTAEKTDKEEEGKVRGANRGLCQRRQVEVKDQQSKQALDLHHPKLMPGSGLALAPST CPRCLFQEGAP |