| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1889 |
Name | ECE1 |
Synonym | ECE;endothelin converting enzyme 1;ECE1;endothelin converting enzyme 1 |
Definition | ECE-1|endothelin-converting enzyme 1 |
Position | 1p36.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Disease | Hypertension;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | atherosclerosis, coronary;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Hypertension, essential, susceptibility to;OMIM |
Disease | ventricular arrhythmia, malignant;GAD |
Disease | Hirschsprung disease, cardiac defects, and autonomic dysfunction;OMIM |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 1889 |
Links to all GeneRIF Items | 1889 |
Links to iHOP | 1889 |
Sequence Information | |
Nucleotide Sequence | >1889 : length: 5259 GTACTCACTGGATGCCTGCAAGTCCAAACATCCTGTTCTTTTTTGAACTCCTCACTGGAG AAACAGGGAAAAGCTGTAGTTTTTTCCTTCCACTCATATCGAGTGACACAAAAAAACAAG CCTGTCGGGGCCGAGCTGCTTGACTCTCTGATGTTTGGGAGCAGATCCGAGCAGCTGAGC AGGGTGGCTGTTCCTTTCCTGGATTAGGGCTGAATCTGTGGGAACCAGACCACCCCTGAG ACAGGAGGCAGCCCTGATGCCTCTCCAGGGCCTGGGCCTGCAGCGGAACCCCTTCCTCCA AGGGAAGCGGGGCCCGGGGCTCACGTCTTCCCCGCCCCTCCTGCCTCCTTCCCTGCAGGT GAACTTCCACAGCCCCCGGAGTGGCCAGAGGTGCTGGGCTGCACGGACCCAGGTGGAGAA GCGGCTGGTGGTGTTGGTGGTACTTCTGGCGGCAGGACTGGTGGCCTGCTTGGCAGCACT GGGCATCCAGTACCAGACAAGATCCCCCTCTGTGTGCCTGAGCGAAGCTTGTGTCTCAGT GACCAGCTCCATCTTGAGCTCCATGGACCCCACAGTGGACCCCTGCCATGACTTCTTCAG CTACGCCTGTGGGGGCTGGATCAAGGCCAACCCAGTCCCTGATGGCCACTCACGCTGGGG GACCTTCAGCAACCTCTGGGAACACAACCAAGCAATCATCAAGCACCTCCTCGAAAACTC CACGGCCAGCGTGAGCGAGGCAGAGAGAAAGGCGCAAGTATACTACCGTGCGTGCATGAA CGAGACCAGGATCGAGGAGCTCAGGGCCAAACCTCTAATGGAGTTGATTGAGAGGCTCGG GGGCTGGAACATCACAGGTCCCTGGGCCAAGGACAACTTCCAGGACACCCTGCAGGTGGT CACCGCCCACTACCGCACCTCACCCTTCTTCTCTGTCTATGTCAGTGCCGATTCCAAGAA CTCCAACAGCAACGTGATCCAGGTGGACCAGTCTGGCCTGGGCTTGCCCTCGAGAGACTA TTACCTGAACAAAACTGAAAACGAGAAGGTGCTGACCGGATATCTGAACTACATGGTCCA GCTGGGGAAGCTGCTGGGCGGCGGGGACGAGGAGGCCATCCGGCCCCAGATGCAGCAGAT CTTGGACTTTGAGACGGCACTGGCCAACATCACCATCCCACAGGAGAAGCGCCGTGATGA GGAGCTCATCTACCACAAAGTGACGGCAGCCGAGCTGCAGACCTTGGCACCCGCCATCAA CTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTAT TGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAG ATGCCTGCTCAACAACTACATGATCTGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGA CCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGAC CTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTT GGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGACAGCAAGAGCATAGCCACCGAGAT CATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGA GGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCC CAACTTCATCATGGATCCCAAGGAGCTGGACAAAGTGTTTAATGACTACACTGCAGTTCC AGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGA TCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGC CTACTACTCGCCCACCAAGAATGAGATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATT CTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCA TGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCG GCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGA GCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGA GAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAA GAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGGCCTCACCAATAACCAGCTCTTCTT CCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCT CATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAA GGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTCACCCATGAACCCGCCTCACAAGTG CGAAGTCTGGTAAGGACGAAGCGGAGAGAGCCAAGACGGAGGAGGGGAAGGGGCTGAGGA CGAGACCCCCATCCAGCCTCCAGGGCATTGCTCAGCCCGCTTGGCCACCCGGGGCCCTGC TTCCTCACACTGGCGGGTTTTCAGCCGGAACCGAGCCCATGGTGTTGGCTCTCAACGTGA CCCGCAGTCTGATCCCCTGTGAAGAGCCGGACATCCCAGGCACACGTGTGCGCCACCTTC AGCAGGCATTCGGGTGCTGGGCTGGTGGCTCATCAGGCCTGGGCCCCACACTGACAAGCG CCAGATACGCCACAAATACCACTGTGTCAAATGCTTTCAAGATATATTTTTGGGGAAACT ATTTTTTAAACACTGTGGAATACACTGGAAATCTTCAGGGAAAAACACATTTAAACACTT TTTTTTTTAAGGAAAGAATTGGTATATTTATTATGTTCTGTTTTTCTAAATAACCTGTGG ACAAGGGAAGCCCCACTGATTTACTCCCTCTCTTCCCCACTCCCTGTGAGGCTGGGCTGA GGCACGGATCCCTGGGCCACAGAGCAAGTCTCCAAATCAGACAGCTGCCTCAGCCCCTGG GATGTGTGATTTCAGCTCCTGTCACCTCATGCAAGGGCGTGGAGACCAGTAGAGGTGTGG AGGCCAGGCAGAGAGAGGAGCCTGCTCTGCGGGGGGCCCAGCTCATGGGCACTGCCCCTT CAGCTAGCCTGCCTCCGTCCCCTGAGTCCAACAGTGGGAGCCCTAGCTGGGAAGTTCTGA TCCCCAAAGCCACAGCAGGGGACTGATGGCTATAGCAGAATGAGGTCGGGTCAGGACCCT CAAACACCATCTGGGAACACCAAGCACCCTGAATCGAGACTGCAGGAGCCCTGCGGGGTG AGACTGTGTCAGAGATACACTGCTGGCCACAAGTGTCCCCTCTCAGTCCCACCTTTTCGG GCTGTCCCATGTCTATCTCAGGGGCCCGTTACCTCTCTGCAGCAGTCCCCCATCCCAGCC ACACCAGGGTCTGTCCGGCCAACCCTCTTCCCCAGGGAAAGGAGAAAAGAGAAAACAGGC TGGGCCCGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGTTGAGGTGGGCGGATCA CCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCATCTCTACTAAA AAAAATTACAAAAATTAGCCGGGAGTGGTGGTGGGCACCTGTAATCCCAGTTACTCGGGA GGCTGAGGCAAGAGAATCTCTTGAGCTCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGC GCCACTGCACTCCAGCCTGGGTGACAGAGGGAGACTCCGTCCCAAAAAAAAGAAAAGAGA AACAGCTGTCACCTCCCGCAGGACCCAAATCCTCTCTCTGAGCACCGTCATCCACCACAT GGCTGGGCCTGGCTCCCAGGACCAGTCCAGTCCTCTAGTGCCTTATCTGAGGCTGCAGCC GCCAGTCTCCACCCCAAGGAGACAGCCCCTGCTCCTAGATGCCCTTGGCCTCCGCAGTGC AGCCCCCAGGTGTCCTGACTGAAGCACAGGCCATAGCCCCATTTCCCCGGTGCCTGCAGG GCTAACCTCCACGGGAGCCCAGGAGCTCTGGCCGGCAGGTCCATGGCACAGGGCATCGGA AGACTGCAAAACTGCTGGACTTACCCTGGGCTGCAGTCCATTGTCGGCCCCTGGGTTGAA TCAAGATAGTACTTGCAGCTAGATGGATGCTTTTAGCCAGGGGACATTGTGAGGGGAAGA TTCCTCCACCCAGTCTGGCCTGTGGTGTCTGTCTCCTCCCTGAGACCACAGCTTCTCCAG TAGCAGACTCATGGGCGCCACCAAGTGGAAGCACCTGGAGCGGCCTCTGCCATCCAGTGG GGAAGCCAGGCCCCGAGACGGAGGTGGGGGCAGCACGTGCCCTCCACAGCCACCGCTTTC CCGCCTCAGCAGCCCAGGCCTCCTGGCCCAGCCCTGCCTGGACAGTGCTCTCCCCTCACC CGGGAAGCTGGAATCCTCCTGCCCGAGAGGAAGCAGACGGCACAGGGACACCCCTGCCAC CTTGGGATCTGCCTCCAAGCTGGTGCAGGGTATCGAGAGTGGATTCCAGATGGAGGTCCT GGTCCCAGCACGCAGCAGTCCTGGTAGCTCTGCAGAGGAGACAGGAACCCGAGAAGTAGC TGAAGCAGAAGCCAGCCGCAGTCCCCTTGCCACATAGAGGCGGGCTTCTCCCAGCCATGG TGTCCCCTCTGCCTCCCCTCCCCCGACCCTCCTGCCTTCCGCGTGGAGGGTGGTGGTCCT GTAGTGTCAGCACCAGCACCATGGGCTTGGACCCCCTCCCTGGACACAGGCAGGTGTCCT AGGGCTGGGGGTGCAGCCCGAGGGAATGGAGACCACACTCATGGCTCAGGTCTGCCGGGG CCGGCAGGGGGTTGGGGAAGAAGAGGGCTCAGGCCCAGCAGGGGTGGAAGCCCCTGCCAC TGCCACTACCCGCTCCAGAGCTTTAAGGAAAATGAAGTGAGACCCCTCCCCTTAGGCCTG GGGAGCCATAGGGCTGGCTTCTCTGTGGGTGCGTGGACGTGGGGTTGGGAGCTGGGAATC TATTTTTTGTATTATGTTTTGAGCTACTGTAGTTTTGGCGTGGCACTATTGTAATGGAAA TAAAATACTTGTACGGAGGGCAAAAAAAAAAAAAAAAAA |
Protein Sequence | >1889 : length: 778 MCMRIIRNAGYKCKFHCPHPRGSNSMSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHSP RSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAALGIQYQTRSPSVCLSEACVSVTSSIL SSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASVS EAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYR TSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLL GGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFL NTIFYPVEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQD ADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIK KAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFE NAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSS PKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNY SVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQ VWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW |