| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1828 |
Name | DSG1 |
Synonym | CDHF4|DG1|DSG|EPKHE|EPKHIA|PPKS1|SPPK1;desmoglein 1;DSG1;desmoglein 1 |
Definition | cadherin family member 4|desmoglein-1|desmosomal glycoprotein 1|pemphigus foliaceus antigen |
Position | 18q12.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | Staphylococcus aureus infection;KEGG PATHWAY;hsa05150 |
Pathway | Apoptotic cleavage of cell adhesion proteins;PID Reactome;500272 |
Disease | Keratosis palmoplantaris striata I;OMIM |
Disease | Eosinophilic esophagitis (pediatric);NHGRI |
Disease | IMMUNE;GAD |
Disease | pemphigus foliaceus;GAD |
Disease | eosinophilic esophagitis (pediatric);GAD |
External Links | |
Links to Entrez Gene | 1828 |
Links to all GeneRIF Items | 1828 |
Links to iHOP | 1828 |
Sequence Information | |
Nucleotide Sequence | >1828 : length: 7262 CCAGCCCAAGTTTTTAGGGTGGGGATCCAGACTGGTTATACGTACCTTCAGTCCTTCTCC CAGAGGAAGGCAGAAACACCTCAAAGCCTGCATGTAAGAACATCTACTGAGAAATTATTT TAATCAGACACCAGCTGAGTGGGAGAAAGAAAAAGAACAGAGAAGAACAAACAAAACTCC CTTGGTCTTGGATGTAAGAGAATCCAGCAGAGATGGACTGGAGTTTCTTCAGAGTAGTTG CAATGCTGTTCATTTTTCTGGTGGTGGTAGAAGTTAACAGTGAATTCCGAATCCAGGTAA GAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTG AATGGATCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGGAACCCAA TCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGCAAGTTACATACCGCATCTCTGGAG TAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTA ATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTC TGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAGAGTCAGGGTTTTGGATA TAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATT CTAATGCAAATACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATT TGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTCAGATTCACCAATGTTTA TTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAAT ACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGT CAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGATAATATCCCTTACATGG AACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGA TTAGAGTAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTA TCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGAAAGAACAAATGTGGGAA TTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTG GTGTCAGAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCAT CTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGTGTTTCGTCCAGGTTCAA AGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTA CTGACCTGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAG CTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTTGAAAAATAAAGTTACCA AGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATA ATCTTCAAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACG ACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATACTGGCAGACAAGAAAGTA CTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTT CTGAACCCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTG GCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGTCCCATTTTTGATGATCT GTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTT CAGATGGAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAA CCACTGTCATACCACAAATACCACCTGATAACGCAAATATAATTGAATGCATTGACAACT CAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGA GAATGACAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTC AAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATGTAGAGAAGGAGGTCTGA ATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATG AAGGACGCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTG CTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGATGACAGCTTCTTGGATA CCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAG ACCTTGATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAG AGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGGCACTACCACAGTAATTT CTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTC TGGGCTATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCT CTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGTGACAGAGAGAGTGGTCG GCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGT CGAATGTTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGA CTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGAAAGAGTAATCCAACCAA CTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCA TTGTGACAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGA TCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCATGGGTGCTGGGAGCGGTG CCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAG CCAGCATTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCG CCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTACCGTGCAATATAGCAAGT AGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACT AAAAAACCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAG GTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCTAGGGGAGAGCTCTCCTT AGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCT TCTTTGTGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAA TTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCTCGAGCAAAATTCAAAAA GAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATG CCCTGTTGGTTTCACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTA ACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCCATCAAGCACTCCTACCT TAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATT CCATTAGAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCT GAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAAGGATTCTTCTGATTCTA GTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAA TATCACACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTA AGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTGTCATCACTAGTGGCAAA TGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGG TGATATTCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATA GGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGTATGCTTAAGCTTTGGGG AATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTG AAAGTTGGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAG TAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCAGGAATCAACCAGGAACC TTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTG CTAGTTTATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGAT TTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAGTGTCCAAATTATATAGT ATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTG TGTGTTTGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAA GAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCTTTCTTAAATACAATGTT ACTATAAGCTCACTAAAATGAAACTCTATATGACAAAATAAAATTAGAAAAAAATTTGCC CTGGAGTTGTGAATTATATACAACTTTTAAAGAATTTACCCCAATTACTCAAATTTCCCA GGAAATTACAAAGCCAAAGAATATTCAACTTCCTCCACTGGTCAAAAGAGGATAGGAGTG AATTACTGAACCTAGAGCTATTTTGCTCTGTAACAACAGATAAGGCTAATATTTTAAAAG CCACAGTATACATCTTCTTTTAACTCTGTAGAATATGTAAAATTTTGATAGTCTGTAGTA TGCTAAATGCAGAAGTATAAATAAAGTCATTCAAAGGGAGTCTTTTCTTTTTCTGACACT TAGGGGGCCACATTAAGGATGGGTAATCTTTCCAGGAATAAAGTCAAAAGGTATTTATTA AGACATACTTGAGTATGCCTGGGTCCAGGAGTTTTAAGGAATAGAAATAAGTATTAATGA ATTAATTAAGTAATTTATTAAAGGGAATGGTAGCTGACCACAGGAAACTTGCTTACTGTT TTGATATGAAATATCATCACAAGCTTTTCTTAAGACATCTGATATCTTCCAGAGATATTT TTTAGGTTGTCTTGCAAACAACAAAATCACTGTCTTTAATAACTGTTGCTGTCAAAATCC ATTGGTTGTTAAGATCCCCCCAATTTAGTTACATCTGAACTCCTAAACACTGTTAAACGA TGGGAAAAACAAGAAAAAACATGGCCATTTGAGTCATTGAGTCATCTATCTTTCTAGGAA GATACTTTCTAACCAAACTTTTCTTCCAGGATTGCAAATTGATGGGAAAAACAAGAAAAA CTGAAGTATTAGTCACCTATCTTTCTGGGAAGATACTTTCCAACTAATTTTTTCTTCCAG GATTGCACACTGATTTTCCATTTAGTCCTAAATTTTAAAATTCCCTTTTCAAGACATCAA CGATTTTAGTAGTTATTTAAAGGCATGTCATTTTTCAATGAAGAAGTTTTGGGCAGAACT TCATTCTTCTTCTTAGATGTTTACTCTAGATCATATACATCATGTCATAGACCAAGAAGA GATATGGAAATTATTTTATAAGTGAATACTATAATTAGGATTCAAGCTGAGTTTCAGATC AACTTGCTCTTAACAAAAGGAAAAAGAAATAGTAATTTAATACTATGTATGTATGGTTTG AAAACAAACCACAATGTTTATAAAATATCTATCTGACTGTCTAAAGAGGTAATCTTTAGG AGCAAAAATCAGTGTATTATAAATACTTTACCATTTAATATCAACCAAAATACCATCTCA AGCTAATTTTGACACTGAATTACAGATATATCTGCTACATATTATTTACTTCTAAGCATG TTGTCTGATGTAATTGCATTTGCACTGAAAAATTAAAAGAAAAAGTACATATTTAGGGTT ATTTATATATCTTCATCTAGACATCTGTTCTACATTTGTGTATAAAGTTTTTAGCATCAT AATTTTTATTCAAGAAAATGTTCTGACAAAATTTTAATTATATGTCTTCAAAAATTACAT TTTTTACTCTAGTAAGTAGATGTTTTTAGTTATCTGGCAATTTATTTCTGAATTTATACC AATGTTTGATTGTCATGGTACAAAATATATGACACCCTTTAACTTTTGCTGGAGTTGAAA GGCATTATAATCTTTAGCATAAATGGCCATGACTATTTTGGAAAGACATTTAAGACCCAA AGCAAACTTTTAAAAGTATTTGCCACATTTTCCCATGCCTATTTCATAAATTCCAACTTT TTTTTTTACAATTTCTGGATTTTTAAGACCCATTTCACATTGCACTAGGATACAGCAGTC CACAGTAGAGTGCTACTCTCCTTGAAATCAAATCTGTCTTCCACTTCCGGATTATTCAAT TTATGTTAGGACAAATCTTGACTAGATCAACCTGTTTTCCATCAGATAATTTTAAAACAA TGTGTAATCTTGTTTGTCTACATTCTCTCCCCAGTTTAGCTGTATTTGAATTACTAAATG CTTTATCGTCAAACTGTACCTAGTCTAACTTATTTTTCTTTTGCTGTCGTTTTACAAGCA TTTTAAAATTCTAATATTCATCTCTGGTGGTGTTTAACACAAGGTTCTCTTATTCAAGTT TCAATATAAAAGTTTTTGGATTATTTGGGTGCTAGTTTCTTGCTTGGTTATCTGTTCGTT TTTTTAAGTTGATTTGTAATTTCCAAAGAGTTATGCATACAGCAATAAAATTATTAATAT GC |
Protein Sequence | >1828 : length: 1049 MDWSFFRVVAMLFIFLVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACRE GEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVT PFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILN ATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGS DRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFS ANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHS IMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTT VRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTIN INIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLL SDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVE GPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGREMQDLGGGERMTGFELTEGV KTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLI YDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQST EPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTES YTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIA PSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAG VTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGLSSLGGTASIGHMRSSSD HHFNQTIGSASPSTARSRITKYSTVQYSK |