| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 174 |
Name | AFP |
Synonym | AFPD|FETA|HPAFP;alpha-fetoprotein;AFP;alpha-fetoprotein |
Definition | alpha-1-fetoprotein|alpha-fetoglobulin |
Position | 4q13.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | FOXA2 and FOXA3 transcription factor networks;PID Curated;200073 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Disease | AFP deficiency, congenital;OMIM |
Disease | alpha-fetoprotein;GAD |
Disease | Hereditary persistence of alpha-fetoprotein;OMIM |
Disease | Infection;FunDO |
Disease | CANCER;GAD |
Disease | Cancer;FunDO |
External Links | |
Links to Entrez Gene | 174 |
Links to all GeneRIF Items | 174 |
Links to iHOP | 174 |
Sequence Information | |
Nucleotide Sequence | >174 : length: 2408 ACACGACCTCTTCCCCAATAACCTATGGAAATTAAAAAATTTTAAAAAATAAAATAGCTA GTAATATTACAAAACACCCATATGATGCAATGTTATACCATCACTCAATAGCATTTTCAG GGCCATTTGTCCTGTAGGTGTTAAATTTATTAAATACTTATTATATGCCAAAATGTAAAA CATGGCTTTTCTTTACTATTCAGACACTATAAGAAATTTTGAGGAACAAAGGAGATAGAG ATGATGATAAGTGTGGTTGACAGAATTGGGGGAAAAAAGTGATCTTAGAAGAAATTTAAG ACAGTTTAGAATAACAGCACTCAAAGAGTGTAAGAAGTTTGGAGAAGCCTTATTGGAAGA GGAATTAGAACACCTGGAGAAACATACAGTAAGAAGTGATGAAGGTCTACTGAACTGATG AGCTGGAGGAGTTGGAGGGTGAATGTTTCTTGTAAAACACTAAAATATTATTCTGGGCCT CTTTTTCCTGTTCCCAGAGCTTCCATATTGGATTCTTACCAATGTACTGCAGAGATAAGT TTAGCTGACCTGGCTACCATATTTTTTGCCCAGTTTGTTCAAGAAGCCACTTACAAGGAA GTAAGCAAAATGGTGAAAGATGCATTGACTGCAATTGAGAAACCCACTGGAGATGAACAG TCTTCAGGGTGTTTAGAAAACCAGCTACCTGCCTTTCTGGAAGAACTTTGCCATGAGAAA GAAATTTTGGAGAAGTACGGACATTCAGACTGCTGCAGCCAAAGTGAAGAGGGAAGACAT AACTGTTTTCTTGCACACAAAAAGCCCACTCCAGCATCGATCCCACTTTTCCAAGTTCCA GAACCTGTCACAAGCTGTGAAGCATATGAAGAAGACAGGGAGACATTCATGAACAAATTC ATTTATGAGATAGCAAGAAGGCATCCCTTCCTGTATGCACCTACAATTCTTCTTTGGGCT GCTCGCTATGACAAAATAATTCCATCTTGCTGCAAAGCTGAAAATGCAGTTGAATGCTTC CAAACAAAGGCAGCAACAGTTACAAAAGAATTAAGAGAAAGCAGCTTGTTAAATCAACAT GCATGTGCAGTAATGAAAAATTTTGGGACCCGAACTTTCCAAGCCATAACTGTTACTAAA CTGAGTCAGAAGTTTACCAAAGTTAATTTTACTGAAATCCAGAAACTAGTCCTGGATGTG GCCCATGTACATGAGCACTGTTGCAGAGGAGATGTGCTGGATTGTCTGCAGGATGGGGAA AAAATCATGTCCTACATATGTTCTCAACAAGACACTCTGTCAAACAAAATAACAGAATGC TGCAAACTGACCACGCTGGAACGTGGTCAATGTATAATTCATGCAGAAAATGATGAAAAA CCTGAAGGTCTATCTCCAAATCTAAACAGGTTTTTAGGAGATAGAGATTTTAACCAATTT TCTTCAGGGGAAAAAAATATCTTCTTGGCAAGTTTTGTTCATGAATATTCAAGAAGACAT CCTCAGCTTGCTGTCTCAGTAATTCTAAGAGTTGCTAAAGGATACCAGGAGTTATTGGAG AAGTGTTTCCAGACTGAAAACCCTCTTGAATGCCAAGATAAAGGAGAAGAAGAATTACAG AAATACATCCAGGAGAGCCAAGCATTGGCAAAGCGAAGCTGCGGCCTCTTCCAGAAACTA GGAGAATATTACTTACAAAATGCGTTTCTCGTTGCTTACACAAAGAAAGCCCCCCAGCTG ACCTCGTCGGAGCTGATGGCCATCACCAGAAAAATGGCAGCCACAGCAGCCACTTGTTGC CAACTCAGTGAGGACAAACTATTGGCCTGTGGCGAGGGAGCGGCTGACATTATTATCGGA CACTTATGTATCAGACATGAAATGACTCCAGTAAACCCTGGTGTTGGCCAGTGCTGCACT TCTTCATATGCCAACAGGAGGCCATGCTTCAGCAGCTTGGTGGTGGATGAAACATATGTC CCTCCTGCATTCTCTGATGACAAGTTCATTTTCCATAAGGATCTGTGCCAAGCTCAGGGT GTAGCGCTGCAAACAATGAAGCAAGAGTTTCTCATTAACCTTGTGAAGCAAAAGCCACAA ATAACAGAGGAACAACTTGAGGCTGTCATTGCAGATTTCTCAGGCCTGTTGGAGAAATGC TGCCAAGGCCAGGAACAGGAAGTCTGCTTTGCTGAAGAGGGACAAAAACTGATTTCAAAA ACTCGTGCTGCTTTGGGAGTTTAAATTACTTCAGGGGAAGAGAAGACAAAACGAGTCTTT CATTCGGTGTGAACTTTTCTCTTTAATTTTAACTGATTTAACACTTTTTGTGAATTAATG AAATGATAAAGACTTTTATGTGAGATTTCCTTATCACAGAAATAAAATATCTCCAAATGT TTCCTTTT |
Protein Sequence | >174 : length: 609 MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATY KEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEG RHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILL WAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITV TKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKIT ECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSR RHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQ KLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADII IGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQA QGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLI SKTRAALGV |