| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1583 |
Name | CYP11A1 |
Synonym | CYP11A|CYPXIA1|P450SCC;cytochrome P450, family 11, subfamily A, polypeptide 1;CYP11A1;cytochrome P450, family 11, subfamily A, polypeptide 1 |
Definition | cholesterol 20-22 desmolase|cholesterol monooxygenase (side-chain cleaving)|cholesterol side-chain cleavage enzyme, mitochondrial|cytochrome P450 11A1|cytochrome P450(scc)|cytochrome P450, subfamily XIA (cholesterol side chain cleavage)|cytochrome P450C11 |
Position | 15q23-q24 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Steroid hormone biosynthesis;KEGG PATHWAY;hsa00140 |
Pathway | pregnenolone biosynthesis;BioCyc;PWY66-377 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Biological oxidations;Reactome;REACT:13433 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | Pregnenolone biosynthesis;PID Reactome;500773 |
Pathway | Endogenous sterols;PID Reactome;500195 |
Pathway | Hormone biosynthesis;Reactome;REACT:15314 |
Disease | Adrenal insufficiency, congenital with or without 46, XY sex reversal;OMIM |
Disease | Genetic disorders;KEGG DISEASE |
Disease | lung cancer;GAD |
Disease | advanced prostate cancer;GAD |
Disease | breast cancer;GAD |
Disease | prostate cancer;GAD |
Disease | CANCER;GAD |
Disease | Lipoid congenital adrenal hyperplasia;OMIM |
Disease | Inherited disorders of lipid/glycolipid metabolism;KEGG DISEASE |
Disease | Congenital adrenal hyperplasia;KEGG DISEASE;H00216 |
External Links | |
Links to Entrez Gene | 1583 |
Links to all GeneRIF Items | 1583 |
Links to iHOP | 1583 |
Sequence Information | |
Nucleotide Sequence | >1583 : length: 2010 GCTAGCGACAGACCCAGCATTCCTCCCAGCGCACGCCGCCGCCCGGGCCGCGCTATTCCG AAATTGGGTCCGCCCTAGCGTGGCCCCCGGCCTGCTCCTGCGCTCTTCGCGGGTCGCTCA CCTCCGCCTCCCCTCGACACAGCCCGAGCCCATCCGCCCCCCGGGTCGACCCGCGTTTAC CTCAGGGCGAGGTCCAGGCGCTCGGCCCCGCGGAGGCGGCGGCGGCCCCACCGCAGGTTC CTAGGTCCCAGTCACTCTGCCGCCAAGTTCCCCAACACGGACTCCGTGCGCTTTGAGGTG TTACGGGGGCGCTGGAGCACTGGCTTCGCTGGCCCTGCCAGGAGGCGGCGGCGAAGCAGG GAGCGACCCGGTATGCGTTTCTCTGCCCGGCCTGCGGCCCTGCAGCATCCACTCCTCGCC TCTGCTGGCCTCTGCCCTCGCTCGCTGCGTTCACCCGAGCTCACCCGAGCCCACCGGAGC CGACAGTGGCGCGCTAAGGGAGAAGCTCGGCAACGTGGAGTCGGTTTATGTCATCGACCC TGAAGATGTGGCCCTTCTCTTTAAGTCCGAGGGCCCCAACCCAGAACGATTCCTCATCCC GCCCTGGGTCGCCTATCACCAGTATTACCAGAGACCCATAGGAGTCCTGTTGAAGAAGTC GGCAGCCTGGAAGAAAGACCGGGTGGCCCTGAACCAGGAGGTGATGGCTCCAGAGGCCAC CAAGAACTTTTTGCCCCTGTTGGATGCAGTGTCTCGGGACTTCGTCAGTGTCCTGCACAG GCGCATCAAGAAGGCGGGCTCCGGAAATTACTCGGGGGACATCAGTGATGACCTGTTCCG CTTTGCCTTTGAGTCCATCACTAACGTCATTTTTGGGGAGCGCCAGGGGATGCTGGAGGA AGTAGTGAACCCCGAGGCCCAGCGATTCATTGATGCCATCTACCAGATGTTCCACACCAG CGTCCCCATGCTCAACCTTCCCCCAGACCTGTTCCGTCTGTTCAGGACCAAGACCTGGAA GGACCATGTGGCTGCATGGGACGTGATTTTCAGTAAAGCTGACATATACACCCAGAACTT CTACTGGGAATTGAGACAGAAAGGAAGTGTTCACCACGATTACCGTGGCATCCTCTACAG ACTCCTGGGAGACAGCAAGATGTCCTTCGAGGACATCAAGGCCAACGTCACAGAGATGCT GGCAGGAGGGGTGGACACGACGTCCATGACCCTGCAGTGGCACTTGTATGAGATGGCACG CAACCTGAAGGTGCAGGATATGCTGCGGGCAGAGGTCTTGGCTGCGCGGCACCAGGCCCA GGGAGACATGGCCACGATGCTACAGCTGGTCCCCCTCCTCAAAGCCAGCATCAAGGAGAC ACTAAGACTTCACCCCATCTCCGTGACCCTGCAGAGATATCTTGTAAATGACTTGGTTCT TCGAGATTACATGATTCCTGCCAAGACACTGGTGCAAGTGGCCATCTATGCTCTGGGCCG AGAGCCCACCTTCTTCTTCGACCCGGAAAATTTTGACCCAACCCGATGGCTGAGCAAAGA CAAGAACATCACCTACTTCCGGAACTTGGGCTTTGGCTGGGGTGTGCGGCAGTGTCTGGG ACGGCGGATCGCTGAGCTAGAGATGACCATCTTCCTCATCAATATGCTGGAGAACTTCAG AGTTGAAATCCAACACCTCAGCGATGTGGGCACCACATTCAACCTCATTCTGATGCCTGA AAAGCCCATCTCCTTCACCTTCTGGCCCTTTAACCAGGAAGCAACCCAGCAGTGATCAGA GAGGATGGCCTGCAGCCACATGGGAGGAAGGCCCAGGGGTGGGGCCCATGGGGTCTCTGC ATCTTCAGTCGTCTGTCCCAAGTCCTGCTCCTTTCTGCCCAGCCTGCTCAGCAGGTTGAA TGGGTTCTCAGTGGTCACCTTCCTCAGCTCAGCTGGGCCACTCCTCTTCACCCACCCCAT GGAGACAATAAACAGCTGAACCATGAAAAA |
Protein Sequence | >1583 : length: 521 MLAKGLPPRSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWL NLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPER FLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVS VLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQM FHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRG ILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAAR HQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIY ALGREPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINML ENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQQ |