| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 157 |
Name | ADRBK2 |
Synonym | BARK2|GRK3;adrenergic, beta, receptor kinase 2;ADRBK2;adrenergic, beta, receptor kinase 2 |
Definition | G-protein-coupled receptor kinase 3|beta-ARK-2|beta-adrenergic receptor kinase 2 |
Position | 22q12.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026 |
Pathway | Olfactory transduction;KEGG PATHWAY;hsa04740 |
Disease | Bipolar disorder;FunDO |
External Links | |
Links to Entrez Gene | 157 |
Links to all GeneRIF Items | 157 |
Links to iHOP | 157 |
Sequence Information | |
Nucleotide Sequence | >157 : length: 10311 ATCTCAAAAAAAAAAGTGCTTGGTGTAAAATCTGGTGCATAGTATGTGCACAATAAATCT CAGCTTTGCTTGCTTGCTTGGTTGATTGATTTTGTCTGTACTGTACTAAACTTAGTTTGG GGACTAAATATACAAATACAAATCATACATATATACCCATTGTTTTTAGGAGCCTACGTC TTCTGGGAAAAGCAGGTGTGTTTGGTAATTAGAAGTGTTTGATAATACCCAGGGAGGTAT TTATAAGCACTGTGGGTGTCTAGTGTGCTGGGCCTAAATCAGCCTGAAAAATAAGAGGTA TCATCTGTGGATTTTCAAGTCCTTTATCCCATTTAACCCCCTAGAGAACCCTGAGAGGTT GGAAATATTGCCCCATTTCAACAGAAGGCCCAGAAAAATCAAGGCACAGTGGCCAGCATT CTCTGCTGCACCTGGAAGGTACTAGACACCCTGAGGCATCCTTGCTAGCGTACTCCTCAT GGGTGAGGCCTAAGCTGTGGCCACTGCAGAGGTCCAGATACTTCCAGGAAGGTCTGATTG TCAGTGAGGCAGTCTCTGTGTGCAGCCAGGAATCTCTGAGTGCAAAGGACAGAGGAATAG AAATCTAGCAGGACAGGCTTGGCTCCAATCCCACATCTCAGGGCCAGAGAGCAGAAGAGA TTCTGAATGGAGTGAGATGACCATCTCTGGTCTCTTACTTAGGCCCAGTCCACAGGCTCA TGTCTGGGGCCCCGGGGGAGTGAGGGCAGCAAAGAAGAACAGACAATGGGCTCCACGCAG ACCTCTGCAACACACTGGAGCCTGAGCCCAATGCTGCACGACCCATCAACTACAAGAAGG AGGGAGAAGGTGTATGACCCCCCCTACACCCGCAACTCTCCCATGATCTCCATGGAGACC CAAAGATATACACTGCAGCACCCAGCAAAGATGTGGTACTTGGTAAGGACAGTGGTACCC ACCTGTTCCACAGGGAACATACTAATCATGTCTGAGATAGCCCCTGAGATGGGCTTGAAT ACCCGGCTGTGGAGAAGTTATAAGAGCTGAGGTCCTATGGAGCCAAGAGGCAGTCAAGTT GGTATTTATTTATGCATTTACAACTATTAATGGGGCACCTTTTATGCCCACAGACTGCTG AGGCCCGGATTAAGCTAGCACAAGAGTTTGATAAGAGGACAACTAACCCTGTGCTTTGAA AATCCAATTCACATTTCTTGAGTATGACTATGTCCTAGGCAGTGGGGATATAAAGGAGAA TAACATAACACCATCTATTGGAGACACCAATGAGAAAACCAGAATTGTAGTTCAACGCAA TAAAGGCTATGCTGGTAATACTTGTGATAATCCCTGAACCAACTGGTATGGCCAATCATA GGCATGAGATCTCAGCTAGTCCAGTCAGAGTGAATCTCAGAGCTCTTTACTGTCTAAAAA GCTTGTTCTTTTTTCTTCTAGGTGTTGGAGTGTGGATATGAGTCATGGAACTCTGGGGCT ATGTTGCTGCCAGTATCCGGAGTGTGATGCAGAAGTACCTTGCAGAGAGAAATGAAATAA CCTTTGACAAGATTTTCAATCAGAAAATTGGTTTCTTGCTATTTAAAGATTTTTGTTTGA ATGAAATTAATGAAGCTGTACCTCAGGTGAAGTTTTATGAAGAGATAAAGGAATATGAAA AACTTGATAATGAGGAAGACCGCCTTTGCAGAAGTCGACAAATTTATGATGCCTACATCA TGAAGGAACTTCTTTCCTGTTCACATCCTTTCTCAAAGCAAGCTGTAGAACACGTACAAA GTCATTTATCCAAGAAACAAGTGACATCAACTCTTTTTCAGCCATACATAGAAGAAATTT GTGAAAGCCTTCGAGGTGACATTTTTCAAAAATTTATGGAAAGTGACAAGTTCACTAGAT TTTGTCAGTGGAAAAACGTTGAATTAAATATCCATTTGACCATGAATGAGTTCAGTGTGC ATAGGATTATTGGACGAGGAGGATTCGGGGAAGTTTATGGTTGCAGGAAAGCAGACACTG GAAAAATGTATGCAATGAAATGCTTAGATAAGAAGAGGATCAAAATGAAACAAGGAGAAA CATTAGCCTTAAATGAAAGAATCATGTTGTCTCTTGTCAGCACAGGAGACTGTCCTTTCA TTGTATGTATGACCTATGCCTTCCATACCCCAGATAAACTCTGCTTCATCCTGGATCTGA TGAACGGGGGCGATTTGCACTACCACCTTTCACAACACGGTGTGTTCTCTGAGAAGGAGA TGCGGTTTTATGCCACTGAAATCATTCTGGGTCTGGAACACATGCACAATCGGTTTGTTG TCTACAGAGATTTGAAGCCAGCAAATATTCTCTTGGATGAACATGGACACGCAAGAATAT CAGATCTTGGTCTTGCCTGCGATTTTTCCAAAAAGAAGCCTCATGCGAGTGTTGGCACCC ATGGGTACATGGCTCCCGAGGTGCTGCAGAAGGGGACGGCCTATGACAGCAGTGCCGACT GGTTCTCCCTGGGCTGCATGCTTTTCAAACTTCTGAGAGGTCACAGCCCTTTCAGACAAC ATAAAACCAAAGACAAGCATGAAATTGACCGAATGACACTCACCGTGAATGTGGAACTTC CAGACACCTTCTCTCCTGAACTGAAGTCCCTTTTGGAGGGCTTGCTTCAGCGAGACGTTA GCAAGCGGCTGGGCTGTCACGGAGGCGGCTCACAGGAAGTAAAAGAGCACAGCTTTTTCA AAGGTGTTGACTGGCAGCATGTCTACTTACAAAAGTACCCACCACCCTTGATTCCTCCCC GGGGAGAAGTCAATGCTGCTGATGCCTTTGATATTGGCTCATTTGATGAAGAGGATACCA AAGGGATTAAGCTACTTGATTGCGACCAAGAACTCTACAAGAACTTCCCTTTGGTCATCT CTGAACGCTGGCAGCAAGAAGTAACGGAAACAGTTTATGAAGCAGTAAATGCAGACACAG ATAAAATCGAGGCCAGGAAGAGAGCTAAAAATAAGCAACTTGGCCACGAAGAAGATTACG CTCTGGGGAAGGACTGTATTATGCACGGGTACATGCTGAAACTGGGAAACCCATTTCTGA CTCAGTGGCAGCGTCGCTATTTTTACCTCTTTCCAAATAGACTTGAATGGAGAGGAGAGG GAGAGTCCCGGCAAAATTTACTGACAATGGAACAGATTCTCTCTGTGGAAGAAACTCAAA TTAAAGACAAAAAATGCATTTTGTTCAGAATAAAAGGAGGGAAACAATTTGTCTTGCAAT GTGAGAGTGATCCAGAGTTTGTGCAGTGGAAGAAAGAGTTGAACGAAACCTTCAAGGAGG CCCAGCGGCTATTGCGTCGTGCCCCGAAGTTCCTCAACAAACCTCGGTCAGGTACTGTGG AGCTCCCAAAGCCATCCCTCTGTCACAGAAACAGCAACGGCCTCTAGCACCCAGAAACAG GGAGGGTCCTCGAGGAGGACACACCAGGGTCTCAGCCTTTTGGGGTGAACGAGGATGAGG CATCTGATCTATTCGCTACCGGGACTCCTCCAGGCTCCCGAGAGGAGTCGGGACCCTTCG GCTTGGGGTCAGCTCAGCTCCCTGCCTTGTCACATTTGTCTGCATTAGAAACTACTGAAG AAATAAAAGTTCTTTTTCTTTGCTACACACTTTGGTACCTATGAACCTAGAACTTGAAGT GACTCCTACTTATCACGTAAATTTTTATGTCTGATATCAAACACATCTTAGACTCCCCAG AATGGAATTTAAAGATGTTCAGTGTTGGGTAACAGATTGCCCTAAGCATTGCCACATATT CTGTCTAGTCACTGCTGATTTTCTATGTCTTTGCTCCATACTGCTGGGGGATGGGAGAGC CACAGTGTGTTTCTTTTGTGCACTTCGCAACTGACTTCTTGTCCTGGGGTTAAAAGTTGA AGATATTTTCTGATGATATTAAAAGTTGAAGATATTTCTGCACTTGGGCCCTCCTCTGGG AGCCGCACCCACATGACTGCCCTGCCTCTGACCAGTCTGTTCCGGGGCCCCCTCAGCCAG GTGGGAATGACGGACACGTACTATCCAAGTGTATGGGATTAACTAATCATTGAAGGCATT CATCCGTCCATCATTGGAAAGATTTACAGTGATTCTGAAGGACAGGCCGTGGAGTTTTAG GTTTCAGGGGCAAGAGCAGTTTTCAAAAGTCTTTGAGTCCAGTGTGCACGAGTCGACAAG CAGTACCTGGCATGCAGGAGCACTCATGGGTGAGTCCGTCTCAGGTCTCGACAATTAGCA GTTGTGTGACAGTCATTCTGGTTCCTTCTGCCTGACCCTGGGAGACATATCAGTAATGGA TGTACAAAAGCAGGTCTGTTTTATGTCTTAGTATAATTTCAGATGAATTGTATTGAAAAA ATGCTGAGGAATGAATGTGTCAAAATGGGTTAACTGTGTATATTGACTTTCATGTCGTCA TGCATCTGTCATGAATGAATGATACTTTGCACTGGGCTGTACGACAGTGAGGACCTTAGG GCATGAAGCCTTTTTCCTGGTCCCAGCAGCATCTGCCCTGTGAAGTTTGTTTTCTCCCAC TGCCTCCAGGCCCCACTGATACCCCCAAATAGATGCTGGGTTATGAGAACCAGCGAAATC CCCCATGTCATCAGTCTTAAAAAAAAAATTTTACAAATCCACGTATTTGTCCCATTCTTG GAGTAGTTTTAGTGTATGTCTTTACATTAACTACTAACAGTATAAATAACTTGACATCGT AATTGTCTGCATCCTGTCCTTGATATTTTTAGCAGTTCCAAATCTTTGTTTTTGTATTTG TTTGCTGTGTTCATGGGCAAAGTAAGTACTTTTTAATGCAGTTATTTTGAGAGTTTGGAA GATAATTACCAAAAGGGTCCATTATTTCATAAGAGTTACTTTGCAAAAAAAAAAATGTGG GTTTTTTTTTTTGTCTATCTCAACTACTAGTTGGGGTTTAAATTAACATACATTTTCTAC TATCTGTTATTTCCAGTGTGGGAGGAGGGATGTACTACTTACATGCATTCTCCTTATTTA AAAAGGAAGAATAGTATTCAAATTCTGTTGAAACACACACACACACACACACACACACAC ACACACACTCCAGAAGCAGAAAAGCCATTGTTCTTAAAGAGTGAATGTCTTCCCAGCCCT GGTTAATTATAGCTGTGACTGATGCCGTTCCCGTCTGCATCTCAAGCTCATAGGTTCTCA GCATGTGCAGTTGAGGATGCGCTGGGCCTCATGCCTGTTCTAGATCTCCAGGATAAAGGG CCTGCTGTTGACTCCACCAGGGTCTGGGCTTAGCGTCTAATATCTCGTACCTAGGGCGTG AGCTGCACAAACGTGTTCAGAAAGATTATTCAACTTTCCCATACTTGTTCTAAAATTGAG CTGATCCGCATCTCTTTCAAAAACTAGAATTTCTGCTCTAAGAATAGAACATAAGGCTCC ACTCCCTTTTAGAAAAGATATATGAATTGGAAAATGCTCTGAAAGTCCTTTTGCTTCAAA CAAAAGTGTAAACTTTTACACTTCCCCAACTCACATTTGATTTGTAATGATATGGTTGAG AAGTACATCTAGATGTCATTTATTAAAAGTGCTTTGTAAGACTAGATTGAGCTGTTTCTG AGGGCGGTCACCAGTTGTGTTGGGGTCTGGTTTGAGTGCCTTCTGCCAAAATGTTGTGAT GGAGGTGTTTCTGCGACCAGACACAGGATACCGCTGTGTCTGCACCCGGTTGCCTGCATG GCCAGAGGAAAAGTCAGTTGGATTAAACATCATGGTATACTTGGCTGTTGTTTTTTTTTA ATTTTTTAATTTTTTGGGATAGGGCCTCGCTCTGTCACCCAGGCTGGAGAACAGTGGGAT GATCATGGCTCACTGCAGCCTTGAATTCCTAGGTTCAAGCAATCCTCCCACGTCAGCCTC CTGAGTAGCTAGGACTACAGGTGCATGCCACCTTTCCTGGCTAATTTATTTTTTGGGTAG AGATGGGGTCTTGAACTCTTAGGCTCAAGTGATCCTCCTTCCTTGGCCTCCCAAAATGCT GGAATTAGAGATGTAAGCCACCATGCCCAGCCATAGTACTTGGATGTTTTAGAAGGTTTT CCAAGTATTACATAATTCCTAGATGTTCACCCTTATTACACTCCAACTATTAAAAAGGTC AAAATTCAGCCTATTTTTTTTCATTATTTTAGATTCCTGTGGTTGGGATATTTTAACATT GATGAGAAAAATAATTGAGGTTGATATTTTTACAAAATCATGCGGTAATAAGTCTTGATT TCATGATTCAAAAGAATCAATAAAGCCTAAAAATAATAGATTACTTTAAGCTGCTATGTA AGATATATATGGAATAAATTAAAAACCTTTGTGAATTCAGGTTTATTATTTTTAACCTAA AACATTCTCTTTGGTTCATTCATCCCCTCATGTCATGGGGGCTCATTGGTTTTCCTTCTT TGTCATATTTAAGTATGATTTTTCAACAAAACTTCTAGAAGTCAGCTTATTATGTCACCA TTCATGCAAAGTGCTCATGCCTCTGATTGGTCCATTCACTGACGTGACAATTTCAGGTCC TATGTTTAAAAAGAAGGGGCTGGCCGGGCACGATGGCTCACGCCTATAATCCCAGCACTT TGGGAGGCCGAGAGGGGCGGTTCACGAGGTCAGGAGATTGAGACCATCCTGGTTAGCAGA GTGAAACCCCGTCTCTACTAAAAATACAAATAAAAATTAGCCGGGCGTGGTGGCGGGCGC CTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGGCAGA GCTTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCT GTCTCAAAAAAAAAAAGGAGGGGGGCTAAATATCCAGTGAGATGCACTGAGGAAAGGAAG CATTTTGCTGAAGACAGCAGCAGCAACAAACAATGGTCTGTTTGTTGCAAACAAGATGTA GCTTGATTTCTGGTCTGACATATGCCATATACAGATATTAGAAACGACTGTTTGAAGGCC ACACTGGTCATCTACAAAGTAATGTTTACCAATTGACGACAGGGATTTAACTAGATTAAA AAGATCAAAGTGTGGTTTTTCTCTGCTTTTTAAAATTTCACTCGGAATTTGTAGCTGGGC CAATTCAACACATTTTACTTTTCAGTGGAATTGATTTTTCTAATGTTTCAGAATTTTAAC ATATCAAGAAGAAAACAACGTTCTCAAAGTCTGGCCTCTTTAGCATGATGTAAACCTATA GAAATGCTTTGAAATGTGCTGGTGTAAGATAAGAGTTATCTTGTATGATTTAATCATATG CAGTGTTGTCTCAGTTACGTTCAGGGAAATGTTTCTGTGTCATTCAGAGATGCTTGATGA ATTAACACCTCCCACCCTGAGTGAGGGGTTGACTTGTTGGGAGATGATTTGGGCTTCACT GGGATCTGTGACAGGTGGGGGCTGGGCTGGGTGTCACAAAGAGAATAGTGGTAGAAATCG GGCGAAGGAAGAAAGAAGTTACTGGTAAAAATCATTACACCATAAAGCACCAAGGAAATA ACTGAGTTAAAATAGGTGAAGTTTCTTTTTTCCCCCCTGTAACAGGAGAGTTTTCCTTAT GATAATTATTCTGAGACTTGGTCACTTTGTTTTTGAATGTGGAGCTGCTGAACTCATTCA GAAGCCATTTGCTGCCTATCAGGACTTTCTGAAGAAGTTCTTTTGCCTCTGCCTACCCTC TGGCACCCTCCCATGGAGGCACAGGGGACCCAGAGCTAAAGCATTACCAGGCCATCTCCA AAACACCCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACTTT GCAGCCCCCGAGGTGGAGAGGCAGTGTCTGGATCACTGTGAATGCATTGCCCCATTGGTC AGTTGGGGACACTGTTACAAATCCACTGAAGTCCTGGTAAAACTGTCAAGAGTAACAGGC CTCTTCTGTTCTACCCTGCTCACTTCCACGGTGAGTTACCAGCCTGGGCAACACAGCAAG ACCCCATCTCTACAAAAAAAATTTTTTTAAGTAATTAACCGTTTAAATTTTTTCCTAAAG ATTTAACATGATTTTTCCCTCCTATGTAAAGTTTACTGGAGAGACTTGAATTACTTAAAT TCATGTTAATATGATTTTTTTTTAATCCAGGTCACATTTTAACAAAGTTTATTATGAAAC AAATGAAATTTGAACTCTAAAATGGTACTCCTTGGCTTCCTCAAGTCACAATGAACTTTA TATTTTCTTTGTCCTTAAGGACTAAGATAGTTGTTTTATTTCAGCCGAATCACAGAGATA ACCACTCCTGCAGGCCCCCACAGCTGGCCCAAAGGGGCTGTCTTTCTGACCTGGCTGTGT TAGCACTGATTGAGAAACGCAGGCTCCCAAATTTTAAATTGCCTTTATTAAAAACACAAA CTACAGAAAATGGGTTAAGAGTATACGCATTTCATCAAACACATATAGGGGAAAAAATCC TTCAATTTAGAGTTAAATAACTCAGCTTTGTATAGTAGAGTTAGCGCTCCAGTATCTAAC AATCTCAGAATCATCTCTGAAAACTGGTAACTATGCTTCCATTTTTAATTTTGTCCTAAA TATCAGATGTCTTTGATGTAAGGGTAGGGAATGGAGAAATATTTTCAATTGTGTATTTGT ATTACAAAGAACTTGAAATTTACTTTCTTAGTTGATTATATTAAATGATGTATATATTAT ATGTGGTTTATAAGCTCAACACTGGCCATTTTTTTAGTTTTATTGTTAAATGGTATTTTT CTATGTTTAATTATAATAGATCTGGCTTTTTCTGGATAGCATAAAGATCACTGAACTATA TATATATAAGAAACAAGAGTTCTATTTTAGCACAAAGGCATTTTATATTATTTATTGAAT CCATAAGTTTGTTTTCGTCAAAAACATTCCATATTATTTCTGCTCCTTTTTATTTGTATA GTTTGTTATTTAAAGAAATGGCAGTCCTTCCTGTTCTTAATACAATAAAATTGAAATAAT GCACCTAGTAATGTGGCCGACATCTCTTCTCACCACCATGGACTGTTTTCAACAACAGTT GATCTTCTGGTCTGTGCTGAGAGGCGCATGCATGTCTTTCGTCACGTCGGGCAGCACACC TGCTGTGAAATACTGCTTTCATCTACCTCTTCAGAAGGCTTCTTGCTTGTTGACAAGTAC CGCAAAGGCTTTATTCTGGACTGGCTATCTCATAAAAGGATTTCTGTAAGACTTTGCAGT GTCATTCCCTCAGAACCTAGGTTTGTTTCTAAAGCCACGGTATTGTCCAGGAGCCCCTGT GTGTGGGGCAGGTAGCTATCCCTCCCATGTCATTAGTAATCCTTTAGGATTTAAGGTACA ACTGGACAGCATCATTCCTTCCCCTTATTGTGCCAAATCCCCACCATCAGCCTTGCCATT GCCTTAAGATTTGATTATTGCACCCAATTACCTAACCACTAAACAGAAAGGCCACCTTCA CTCTTTGAAAAAGGCAAGCTGTGCTTAGAAACACTGCTTTTAAGAGTAGCACATTTGAGT GTGACTTTTTCCCCCCTTCACTATTTCAAAATGGTTTTGAAATGGGGTCTTAAAGGTAAG CGCCCTCATACATGACTGAAACTTTGTGAGAGGTCTTATATTTGAATGGACCCTTAATGA TTTATGTGAAATAGAATGAAGTCCTGTCTCTGTGAGAGAACGTGCCTCCTCACTCATTTG TCTCTGTCTGTTTTCATAGCCATCAATATAGTAACATATTTACTATATTCTTGAATACCC TTGAAGAAAGAAATCCGTTTTCTATTGTGCATTGCTATACGAAGTGAAGCCAGTAAACTA GATACTGTAAATCTAGATATTGTACCTAGACAAAATATCATTGGTTCTATCTCTTTTTGT ATCTGTTGTGCCAGGGAAGGTTTATAATCCCTTCTCAGTATACACTCACTAGTGCACGTC TGAAATAGTATCCCACGGGAGATGCTGCTCCACGTCTGAGGTCACCTGCCCTGTGTGGGG CACACCACCGTCAGCACCACCGTTTTTACAGTTACTTTGGAGCTGCTAGACTGGTTTTCT GTGTTGGTAAATTGCCTATATAAATCTGAATAAAAAGGATCTGTACAAAGA |
Protein Sequence | >157 : length: 688 MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR APKFLNKPRSGTVELPKPSLCHRNSNGL |