| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1234 |
Name | CCR5 |
Synonym | CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22;chemokine (C-C motif) receptor 5 (gene/pseudogene);CCR5;chemokine (C-C motif) receptor 5 (gene/pseudogene) |
Definition | C-C chemokine receptor type 5|C-C motif chemokine receptor 5 A159A|HIV-1 fusion coreceptor|chemokine receptor CCR5|chemr13 |
Position | 3p21.31 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | pertussis toxin-insensitive ccr5 signaling in macrophage;PID BioCarta;100214 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | HIV Infection;Reactome;REACT:6185 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | il12 and stat4 dependent signaling pathway in th1 development;PID BioCarta;100133 |
Pathway | IL12-mediated signaling events;PID Curated;200034 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Disease | Lupus erythematosus;FunDO |
Disease | IMMUNE;GAD |
Disease | HIV-1 disease;GAD |
Disease | Brucellosis;FunDO |
Disease | Sjogren's syndrome;GAD |
Disease | HIV;GAD |
Disease | Lung cancer;FunDO |
Disease | severe RSV bronchiolitis;GAD |
Disease | Melanoma;FunDO |
Disease | Hepatitis C;FunDO |
Disease | HCV infection;GAD |
Disease | Liver cancer;FunDO |
Disease | Mucocutaneous lymph node syndrome;FunDO |
Disease | Breast cancer;FunDO |
Disease | Aortic aneurysm;FunDO |
Disease | Colon cancer;FunDO |
Disease | hepatitis B;GAD |
Disease | Communicable disease;FunDO |
Disease | Physician diagnosed asthma;GAD |
Disease | Wegener's granulomatosis;GAD |
Disease | Prostate cancer;FunDO |
Disease | Chronic rejection of renal transplant;FunDO |
Disease | nephropathy in other diseases;GAD |
Disease | Multiple myeloma;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | HIV infection;GAD |
Disease | Hepatitis C, Chronic;GAD |
Disease | kidney transplant rejection;GAD |
Disease | Kidney Failure, Chronic;GAD |
Disease | Liver disease;FunDO |
Disease | Asthma;GAD |
Disease | RENAL;GAD |
Disease | Viremia;FunDO |
Disease | Schizophrenia;FunDO |
Disease | INFECTION;GAD |
Disease | Alzheimer's disease;FunDO |
Disease | Cervical cancer;FunDO |
Disease | METABOLIC;GAD |
Disease | Drug abuse;FunDO |
Disease | Encephalitis;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | diabetes, type 1;GAD |
Disease | Cardiovascular Diseases;GAD |
Disease | Hepatitis C virus, resistance to;OMIM |
Disease | Coronary Artery Disease;GAD |
Disease | Celiac Disease;GAD |
Disease | Fetal disease;FunDO |
Disease | Multiple sclerosis;FunDO |
Disease | rheumatoid arthritis;GAD |
Disease | Testicular dysfunction;FunDO |
Disease | Heart failure;FunDO |
Disease | Renal Transplant Survival;GAD |
Disease | Kidney failure;FunDO |
Disease | HIV disease progression;GAD |
Disease | Neuritis;FunDO |
Disease | Graves' disease;FunDO |
Disease | Adenovirus infection;FunDO |
Disease | Inflammation;GAD |
Disease | Chronic obstructive airway disease;FunDO |
Disease | hepatitis C;GAD |
Disease | HIV infection, susceptibility/resistance to;OMIM |
Disease | Hypertension;FunDO |
Disease | Behcet syndrome;FunDO |
Disease | nephropathy, diabetic;GAD |
Disease | Hyperlipidemia;FunDO |
Disease | IGA glomerulonephritis;FunDO |
Disease | Polymyositis;FunDO |
Disease | West nile virus, susceptibility to;OMIM |
Disease | Asthma;FunDO |
Disease | HIV-1 infection;GAD |
Disease | Human Renal Transplantation;GAD |
Disease | Myocardial Infarction;GAD |
Disease | Hemophilia;FunDO |
Disease | multiple sclerosis;GAD |
Disease | Diabetes mellitus, insulin-dependent, 22;OMIM |
Disease | Arthritis;FunDO |
Disease | diabetic nephropathy;GAD |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 1234 |
Links to all GeneRIF Items | 1234 |
Links to iHOP | 1234 |
Sequence Information | |
Nucleotide Sequence | >1234 : length: 3686 CTTCAGATAGATTATATCTGGAGTGAAGAATCCTGCCACCTATGTATCTGGCATAGTATT CTGTGTAGTGGGATGAGCAGAGAACAAAAACAAAATAATCCAGTGAGAAAAGCCCGTAAA TAAACCTTCAGACCAGAGATCTATTCTCTAGCTTATTTTAAGCTCAACTTAAAAAGAAGA ACTGTTCTCTGATTCTTTTCGCCTTCAATACACTTAATGATTTAACTCCACCCTCCTTCA AAAGAAACAGCATTTCCTACTTTTATACTGTCTATATGATTGATTTGCACAGCTCATCTG GCCAGAAGAGCTGAGACATCCGTTCCCCTACAAGAAACTCTCCCCGGGTGGAACAAGATG GATTATCAAGTGTCAAGTCCAATCTATGACATCAATTATTATACATCGGAGCCCTGCCAA AAAATCAATGTGAAGCAAATCGCAGCCCGCCTCCTGCCTCCGCTCTACTCACTGGTGTTC ATCTTTGGTTTTGTGGGCAACATGCTGGTCATCCTCATCCTGATAAACTGCAAAAGGCTG AAGAGCATGACTGACATCTACCTGCTCAACCTGGCCATCTCTGACCTGTTTTTCCTTCTT ACTGTCCCCTTCTGGGCTCACTATGCTGCCGCCCAGTGGGACTTTGGAAATACAATGTGT CAACTCTTGACAGGGCTCTATTTTATAGGCTTCTTCTCTGGAATCTTCTTCATCATCCTC CTGACAATCGATAGGTACCTGGCTGTCGTCCATGCTGTGTTTGCTTTAAAAGCCAGGACG GTCACCTTTGGGGTGGTGACAAGTGTGATCACTTGGGTGGTGGCTGTGTTTGCGTCTCTC CCAGGAATCATCTTTACCAGATCTCAAAAAGAAGGTCTTCATTACACCTGCAGCTCTCAT TTTCCATACAGTCAGTATCAATTCTGGAAGAATTTCCAGACATTAAAGATAGTCATCTTG GGGCTGGTCCTGCCGCTGCTTGTCATGGTCATCTGCTACTCGGGAATCCTAAAAACTCTG CTTCGGTGTCGAAATGAGAAGAAGAGGCACAGGGCTGTGAGGCTTATCTTCACCATCATG ATTGTTTATTTTCTCTTCTGGGCTCCCTACAACATTGTCCTTCTCCTGAACACCTTCCAG GAATTCTTTGGCCTGAATAATTGCAGTAGCTCTAACAGGTTGGACCAAGCTATGCAGGTG ACAGAGACTCTTGGGATGACGCACTGCTGCATCAACCCCATCATCTATGCCTTTGTCGGG GAGAAGTTCAGAAACTACCTCTTAGTCTTCTTCCAAAAGCACATTGCCAAACGCTTCTGC AAATGCTGTTCTATTTTCCAGCAAGAGGCTCCCGAGCGAGCAAGCTCAGTTTACACCCGA TCCACTGGGGAGCAGGAAATATCTGTGGGCTTGTGACACGGACTCAAGTGGGCTGGTGAC CCAGTCAGAGTTGTGCACATGGCTTAGTTTTCATACACAGCCTGGGCTGGGGGTGGGGTG GGAGAGGTCTTTTTTAAAAGGAAGTTACTGTTATAGAGGGTCTAAGATTCATCCATTTAT TTGGCATCTGTTTAAAGTAGATTAGATCTTTTAAGCCCATCAATTATAGAAAGCCAAATC AAAATATGTTGATGAAAAATAGCAACCTTTTTATCTCCCCTTCACATGCATCAAGTTATT GACAAACTCTCCCTTCACTCCGAAAGTTCCTTATGTATATTTAAAAGAAAGCCTCAGAGA ATTGCTGATTCTTGAGTTTAGTGATCTGAACAGAAATACCAAAATTATTTCAGAAATGTA CAACTTTTTACCTAGTACAAGGCAACATATAGGTTGTAAATGTGTTTAAAACAGGTCTTT GTCTTGCTATGGGGAGAAAAGACATGAATATGATTAGTAAAGAAATGACACTTTTCATGT GTGATTTCCCCTCCAAGGTATGGTTAATAAGTTTCACTGACTTAGAACCAGGCGAGAGAC TTGTGGCCTGGGAGAGCTGGGGAAGCTTCTTAAATGAGAAGGAATTTGAGTTGGATCATC TATTGCTGGCAAAGACAGAAGCCTCACTGCAAGCACTGCATGGGCAAGCTTGGCTGTAGA AGGAGACAGAGCTGGTTGGGAAGACATGGGGAGGAAGGACAAGGCTAGATCATGAAGAAC CTTGACGGCATTGCTCCGTCTAAGTCATGAGCTGAGCAGGGAGATCCTGGTTGGTGTTGC AGAAGGTTTACTCTGTGGCCAAAGGAGGGTCAGGAAGGATGAGCATTTAGGGCAAGGAGA CCACCAACAGCCCTCAGGTCAGGGTGAGGATGGCCTCTGCTAAGCTCAAGGCGTGAGGAT GGGAAGGAGGGAGGTATTCGTAAGGATGGGAAGGAGGGAGGTATTCGTGCAGCATATGAG GATGCAGAGTCAGCAGAACTGGGGTGGATTTGGGTTGGAAGTGAGGGTCAGAGAGGAGTC AGAGAGAATCCCTAGTCTTCAAGCAGATTGGAGAAACCCTTGAAAAGACATCAAGCACAG AAGGAGGAGGAGGAGGTTTAGGTCAAGAAGAAGATGGATTGGTGTAAAAGGATGGGTCTG GTTTGCAGAGCTTGAACACAGTCTCACCCAGACTCCAGGCTGTCTTTCACTGAATGCTTC TGACTTCATAGATTTCCTTCCCATCCCAGCTGAAATACTGAGGGGTCTCCAGGAGGAGAC TAGATTTATGAATACACGAGGTATGAGGTCTAGGAACATACTTCAGCTCACACATGAGAT CTAGGTGAGGATTGATTACCTAGTAGTCATTTCATGGGTTGTTGGGAGGATTCTATGAGG CAACCACAGGCAGCATTTAGCACATACTACACATTCAATAAGCATCAAACTCTTAGTTAC TCATTCAGGGATAGCACTGAGCAAAGCATTGAGCAAAGGGGTCCCATAGAGGTGAGGGAA GCCTGAAAAACTAAGATGCTGCCTGCCCAGTGCACACAAGTGTAGGTATCATTTTCTGCA TTTAACCGTCAATAGGCAAAGGGGGGAAGGGACATATTCATTTGGAAATAAGCTGCCTTG AGCCTTAAAACCCACAAAAGTACAATTTACCAGCCTCCGTATTTCAGACTGAATGGGGGT GGGGGGGGCGCCTTAGGTACTTATTCCAGATGCCTTCTCCAGACAAACCAGAAGCAACAG AAAAAATCGTCTCTCCCTCCCTTTGAAATGAATATACCCCTTAGTGTTTGGGTATATTCA TTTCAAAGGGAGAGAGAGAGGTTTTTTTCTGTTCTGTCTCATATGATTGTGCACATACTT GAGACTGTTTTGAATTTGGGGGATGGCTAAAACCATCATAGTACAGGTAAGGTGAGGGAA TAGTAAGTGGTGAGAACTACTCAGGGAATGAAGGTGTCAGAATAATAAGAGGTGCTACTG ACTTTCTCAGCCTCTGAATATGAACGGTGAGCATTGTGGCTGTCAGCAGGAAGCAACGAA GGGAAATGTCTTTCCTTTTGCTCTTAAGTTGTGGAGAGTGCAACAGTAGCATAGGACCCT ACCCTCTGGGCCAAGTCAAAGACATTCTGACATCTTAGTATTTGCATATTCTTATGTATG TGAAAGTTACAAATTGCTTGAAAGAAAATATGCATCTAATAAAAAACACCTTCTAAAATA AAAAAAAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >1234 : length: 352 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL |