| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1139 |
Name | CHRNA7 |
Synonym | CHRNA7-2|NACHRA7;cholinergic receptor, nicotinic, alpha 7 (neuronal);CHRNA7;cholinergic receptor, nicotinic, alpha 7 (neuronal) |
Definition | a7 nicotinic acetylcholine receptor|alpha 7 neuronal nicotinic acetylcholine receptor|alpha-7 nicotinic cholinergic receptor subunit|cholinergic receptor, nicotinic, alpha polypeptide 7|neuronal acetylcholine receptor protein, alpha-7 chain|neuronal acety |
Position | 15q14 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Alzheimer disease-amyloid secretase pathway;PANTHER;P00003 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | Nicotinic acetylcholine receptor signaling pathway;PANTHER;P00044 |
Disease | Drug abuse;FunDO |
Disease | Schizophrenia, neurophysiologic defect in;OMIM |
Disease | Myoclonic epilepsy, Juvenile;FunDO |
Disease | Autistic disorder;FunDO |
Disease | PSYCH;GAD |
Disease | memory performance;GAD |
Disease | Alzheimer's disease;GAD |
Disease | Psychotic disorder;FunDO |
Disease | schizophrenia;GAD |
Disease | Neuroblastoma;FunDO |
Disease | Behavior disease;FunDO |
Disease | NEUROLOGICAL;GAD |
Disease | Down syndrome;FunDO |
Disease | Colon cancer;FunDO |
Disease | Parkinson disease;FunDO |
Disease | Bipolar disorder;FunDO |
External Links | |
Links to Entrez Gene | 1139 |
Links to all GeneRIF Items | 1139 |
Links to iHOP | 1139 |
Sequence Information | |
Nucleotide Sequence | >1139 : length: 5903 GCCAGAGTCCCACAGAACCTCTTTGAGAAGGGGGAAAGGGGATGAGAAGAACCAAGTTTT AACCACCAACATTTGGCTGCAAATGTCTTGGACAGATCACTATTTACAGTGGAATGTGTC AGAATATCCAGGGGTGAAGACTGTTCGTTTCCCAGATGGCCAGATTTGGAAACCAGACAT TCTTCTCTATAACAGTGCTGATGAGCGCTTTGACGCCACATTCCACACTAACGTGTTGGT GAATTCTTCTGGGCATTGCCAGTACCTGCCTCCAGGCATATTCAAGAGTTCCTGCTACAT CGATGTACGCTGGTTTCCCTTTGATGTGCAGCACTGCAAACTGAAGTTTGGGTCCTGGTC TTACGGAGGCTGGTCCTTGGATCTGCAGATGCAGGAGGCAGATATCAGTGGCTATATCCC CAATGGAGAATGGGACCTAGTGGGAATCCCCGGCAAGAGGAGTGAAAGGTTCTATGAGTG CTGCAAAGAGCCCTACCCCGATGTCACCTTCACAGTGACCATGCGCCGCAGGACGCTCTA CTATGGCCTCAACCTGCTGATCCCCTGTGTGCTCATCTCCGCCCTCGCCCTGCTGGTGTT CCTGCTTCCTGCAGATTCCGGGGAGAAGATTTCCCTGGGGATAACAGTCTTACTCTCTCT TACCGTCTTCATGCTGCTCGTGGCTGAGATCATGCCCGCAACATCCGATTCGGTACCATT GATAGCCCAGTACTTCGCCAGCACCATGATCATCGTGGGCCTCTCGGTGGTGGTGACGGT GATCGTGCTGCAGTACCACCACCACGACCCCGACGGGGGCAAGATGCCCAAGTGGACCAG AGTCATCCTTCTGAACTGGTGCGCGTGGTTCCTGCGAATGAAGAGGCCCGGGGAGGACAA GGTGCGCCCGGCCTGCCAGCACAAGCAGCGGCGCTGCAGCCTGGCCAGTGTGGAGATGAG CGCCGTGGCGCCGCCGCCCGCCAGCAACGGGAACCTGCTGTACATCGGCTTCCGCGGCCT GGACGGCGTGCACTGTGTCCCGACCCCCGACTCTGGGGTAGTGTGTGGCCGCATGGCCTG CTCCCCCACGCACGATGAGCACCTCCTGCACGGCGGGCAACCCCCCGAGGGGGACCCGGA CTTGGCCAAGATCCTGGAGGAGGTCCGCTACATTGCCAACCGCTTCCGCTGCCAGGACGA AAGCGAGGCGGTCTGCAGCGAGTGGAAGTTCGCCGCCTGTGTGGTGGACCGCCTGTGCCT CATGGCCTTCTCGGTCTTCACCATCATCTGCACCATCGGCATCCTGATGTCGGCTCCCAA CTTCGTGGAGGCCGTGTCCAAAGACTTTGCGTAACCACGCCTGGTTCTGTACATGTGGAA AACTCACAGATGGGCAAGGCCTTTGGCTTGGCGAGATTTGGGGGTGCTAATCCAGGACAG CATTACACGCCACAACTCCAGTGTTCCCTTCTGGCTGTCAGTCGTGTTGCTTACGGTTTC TTTGTTACTTTAGGTAGTAGAATCTCAGCACTTTGTTTCATATTCTCAGATGGGCTGATA GATATCCTTGGCACATCCGTACCATCGGTCAGCAGGGCCACTGAGTAGTCATTTTGCCCA TTAGCCCACTGCCTGGAAAGCCCTTCGGAGAGCTCCCCATGGCTCCTCACCACCGAGACA GTTGGTTTTGCATGTCTGCATGAAGGTCTACCTGAAAATTCAACATTTGCTTTTTGCTTG TGTACAAACCCAGATTGAAGCTAAAATAAACCAGACTCACTAAATCCTTTCCAATAATTG ACTGGTGGAAGGAAAACAAAAAACAAAAACTAAAAACCTCTTAGCTTTTCTGCAGTTCAA CTTTTTATTTTTATTTTTATTTCTATCAAAGACGGTAGAGAGAAACAGCTTGATGCTGTT TCTACATTAAAAAAAAAAGAAAGACAGACTGTTGGTCTTACTAAGGATGTTTTTACCAGC CTGCCTGACTTCTGCAAACCTACCCTGTCAAGGAGATCAAAGGGACGCAGGTTTCTGTTT ATTCTGAACAAGGGCCAGGCCCCGCGGAGTGTCTTTGGTGGATCCCAGATAACTCCTAGG TGCTGCTCTCAGACACTGAGGAGTTGAGCAAATCTGTTCTATTCTGCAGAACCCACAGGA CAAATAAGAGTTCTACTAGAATTAACAGCCCAAAAGAATAGCTACAGCTAAGTGAAGCCA CTTACGTGGGCTTTAAAAAAATAATGTGTTAGCTGATTCACATGCACTGGAGTTAATTAG TCTTAGAAATGTGTGCATCCATACAAATGCACAACATAAAGTGAACATATTCCTAGGCCC TTTCTGCCTGTGTCAGGGCCAGGAAGTAGAGGCTGGGAACTCTTCTGGTCCCCAGTATGG CAGGCGCCAGGGAGGGGATGGTGTGGCCCATCCCTTCTCTGGATACCTGGCCAGTGGCAG GCAGCAGGGAGGAGCTGGCCGACCCTCAGTGACTGACAAGCCAGCAATTCTGAGTTCTGG CCTTTGGGAGTCTGCCTGCTCCAAGCCAGTCCACCCCAGCTGCAGCCCCAAAAGCTGGCT CAAAGTCCTTGGGTGGATTCACTGGAGATGGGCAACTTAAAACAAGAGAAACTTTAATTT TTAAACCTAAGTGATGATACAGCTCTTCCCTTAGATTATCGCCCAGGCTGGAGTGCAGTG GCATGATCTCAGCTCACTGCAAGCTCCACCTCCCGGGTTCATGCCATTCTCCTGCCTCAG CCTCCCCCCGAGTAACTGGGAATACAGGCGCCCGCCACCATGCCTGGCTAATTTTTTGTA TTTTTAGTAGAGATAGGGTTTCATCATGTTAGCCAGGATGGTCTCATTCTTATTCTTTAA TGAGATCAGAGGGTAATTCACCAAGAAAGACCTCTCCTGTTCCATTGTGTCATCCAACAA CTGCTCAGAGCTCAAAATTATAGAAGGCTTCTGAGCCCCTAGAGATTTTTAATTTGCTTC TAATCCCTGAGGTGGGAACATCATGAGGGAAGATTTGATTTTCAGAGTTAAATAAATTGT ATGTGCTTTTCCAGCCATCTGGCTCACTCATTTCTGGGTAATGCACATGACTTTGTTTGC ACTGGAGGAAGATGGAAGCTTGCGTGTGTGCGGTGTGTGTGTGTGTGTAAGTGTGAGGTA CCTTGTGTGTGACAAGAGACCTCACTTACGAGAAAGTTGGTGGATCAGGACATTCCAGCC TCAGGCGGCTTGGAGCAGGATCATTCCTCAGCAGGCATTCCTTCCACATGCTATGGATGA GCCATGCACAAGATTTTCGTTTTTTTTTTTTTTTTCTGTTACAGTGTCTTTAGAAACAAG TAGAAGTGTTTTGATATATAAAAGGAATGCTTCATTTCTTATCATTATCCCAAAATTGAT CCCTCCCACATTTTTGCTTTAAAAAGAAACCTTTTTGGTTTTGTATTTTATACAGGAACA CAAAATGCAAACAAGTTGTGCATATTTTGGACTCTCAAATAACTACTCTGTCCTTTAATA AAGTAATAATAAGGAATAGATGTGCACATAGTTAGAAAAGTATGAGTGGTTAAAAACAAC AGTCTCCCATACTGCCTGTTTTCTCTCTCAGAGGGGACCACTAATGAGCTTCTAAGGGCA TTTCTAGAAAGGAAGAAAAGAAGATAAGAGGCCAAAGAAGGAGGGACGGGGGTTATGGAG AGAGACCTTCCCTTTCCAGCACTAACGCTCTGTGAAGGGCGCTGCACCTTGCATTCTTCA TGTGGTGTTTTGTCTTAGAGGTCGTCCCATAATAACATATAAAGATCTACCTCATTCCTC CTAGTAGCTGCTTAGCATTCCATTATCTCAGCGGACTATCATTTATTTGAATAGCCTTTT ATTGGTGAACATATGGATACTTCCAGTTTTTATTTTTATATACAAATCTATAATTGGCAT ACTTGTACATACATCTTGACATAGTTTTGTGACTAAAACGGTATAAATTCCAACTTAGAA ATGGAATTGCTGGGTTTAAGGCTACATGTATTTAAAATTTTGATAGCTATTGCCAGATTA TCTTCTAGAAACTGATCGAAGGATGTAACTCCATCAAGAGTACAATAAAAGGCCCAATTT CTCAGCTTTCTATAATAGCACTGGGTATTTTCAAACTTAATGTTTTTCCCAATATAATTG GTGAAACATGATATTTACGAATATTATTCTGATTTTGGTTTATTTTGTGTATAAAATGGG ACATCTTTTAAAATTTTTTTGTAGTTTTAATTTTGATACATTTATATATTTTACCCAGTT CCTAATTGGGTTATTTGGCTTTTTCTTAATTTGCTCATGCACTTTGGGACATTTTTGTCT TATGTCTTTAAAATATTTTTATCATTTGTCTTTCGATGTTATTTATTGATTTCCTTATTT ATTGGCATAGAGTTTAAATTTTTATGTTGTCAATTTGTGAGTATTTTTCTTTGTCGATCG TGGGATTTGTTTCCAGTTTTTAAAAGCCTTCCTCATTCTGAGATTATAAATAGACTTACT CGCATTTTCTTCTGAAACTTTATGGTTTTATTGGTTTACCTTCACATCTTCAGACTCCCT GGAATTCATTTGTTGCAGGACATGAGGGAAAAATCCATACTTTTTCCTCGAAATGGTGGT CAGCAGTATCAATAAATATGTAATAATGCATTTCTAAAATACAGTCATAGTGTTTTCCCC AGTTGTTCAAAATGCAGCCTTATTTGTAAACTAAATTTCTTTAAGTGTTTGGTTCTGTTT CTGTTCTATTTATCTCTATGAATGCCTTTCATTTCTAAAGCATTATTCATACTAATATCA GTATTTTCAAGTCAACACTCCCATCAACTCTGAATCTCTCTCTCATATGAATCTTTTTTC AATTAGAGTCACAATGAATTTACAGATTGAGTCTTCCTATTCAAAAGCATGAAATCTTGT GTTTAAGTCTAATTTTATGTAACTTAGTAGTGTTTTATGATTTTGTTCACTAAGGTGCTT TGAATTTATAGTTTATTTCTAGATGTTTTATCATTTGGCTATCATTTTCAATAGAATGAT TTATTCCACTTTATTTTCTATTTTATCCCATTGTATAAGAAAGTAGTTGGTTTTTATGTA TGAATGTTATAATCAACCACAAATTGTGATTCCTACTTGTTTCTAAGGTATACTTTTGAC TTCTCCTTTCCAATGTGTCTCTTATTTCTTTCTTGTATCTAGTTGATTTGAGATCAGTGT TGAGTCACAGTGATTCAGGTGGCATGCTTATCTTGTTCGTGACATCAGTGGGACGTTTTA ATGTCTCAGCGTTTAACTTGTATGAAGACATGTATTTTCCTTGCCATAATAAAAAAGTAT CTGTGTGTTCTCAAACTATTAAGACTCTCTGGGGAAAATGTAGATGTTAGATTTTTGTCA AAGCCTTCTCAGTGTCCAGAGGGATTATCAGAAGGTCTTTTCCTTTGCTCTAGTAGTATG TTTAATTATATTAATAGAATACTTAAGACCAAATCATTAGTGTATTCCTGAGATGTTCTT TACTTATTAGTATCATGACTTTGGTTATCAATATTTATAATTAAGATTCATCATTCTACA TCTTGCTTTTATGTGTTTTTTGTCCAGATTTAACTTTATGCTGACTTAAAGGAAGAAATA TTATAAAACAAAAACCTCTATATTCTACAATCATCTATTGGTTTTGAATTATTTTCTGCT TAAGTGTAGAAGAACTAGCTGGGGCTGTCTGGGCCTGCCGTGGTATATTTCTGGATTTTG CTCATCAGGCAAGTTAGGTCCTCGAGCCCTTCTAGAGTCCATTTTAATGACATTTTTAAA AATAAAATTAATTCCATCCACTT |
Protein Sequence | >1139 : length: 531 MRCSPGGVWLALAASLLHGKATASPPSTPPWDPGHIPGASVRPAPGPVSLQGEFQRKLYK ELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNV SEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCY IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA |