| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1137 |
Name | CHRNA4 |
Synonym | BFNC|EBN|EBN1|NACHR|NACHRA4|NACRA4;cholinergic receptor, nicotinic, alpha 4 (neuronal);CHRNA4;cholinergic receptor, nicotinic, alpha 4 (neuronal) |
Definition | cholinergic receptor, nicotinic, alpha polypeptide 4|neuronal acetylcholine receptor subunit alpha-4|neuronal nicotinic acetylcholine receptor alpha-4 subunit |
Position | 20q13.33 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Nicotinic acetylcholine receptor signaling pathway;PANTHER;P00044 |
Disease | Seizures, Febrile;GAD |
Disease | febrile convulsions;GAD |
Disease | alcohol-related phenotypes nicotine;GAD |
Disease | PSYCH;GAD |
Disease | CHEMDEPENDENCY;GAD |
Disease | chronic obstructive pulmonary disease;GAD |
Disease | Psychotic disorder;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Nicotine addiction, susceptibility to;OMIM |
Disease | Epilepsy, nocturnal frontal lobe, 1;OMIM |
Disease | Parkinson disease;FunDO |
Disease | attentional network function;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | epilepsy;GAD |
Disease | Down syndrome;FunDO |
Disease | Autistic disorder;FunDO |
Disease | Behavior disease;FunDO |
Disease | Epilepsy;FunDO |
External Links | |
Links to Entrez Gene | 1137 |
Links to all GeneRIF Items | 1137 |
Links to iHOP | 1137 |
Sequence Information | |
Nucleotide Sequence | >1137 : length: 5568 TCCCAGCCGGCTGAGGCGGGCAGGGCCGGGCGGGGCCGCGCCACGGAGCCCACAGCCCGG CGCTCCCTGCCGCGCCGCCGCCGCACCGCGCCCCACAGGAGAAGACGAACCGGGCCCGGC GGCCGAAGCGGCCCGCGAGGCGCGGGAGGCATGAAGTTGGGCGCGCACGGGCCTCGAAGC GGCGGGGAGCCGGGAGCCGCCCGCATCTAGAGCCCGCGAGGTGCGTGCGCCATGGAGCTA GGGGGCCCCGGAGCGCCGCGGCTGCTGCCGCCGCTGCTGCTGCTTCTGGGGACCGGCCTC CTGCGCGCCAGCAGCCATGTGGAGACCCGGGCCCACGCCGAGGAGCGGCTCCTGAAGAAA CTCTTCTCCGGTTACAACAAGTGGTCCCGACCCGTGGCCAACATCTCGGACGTGGTCCTC GTCCGCTTCGGCCTGTCCATCGCTCAGCTCATTGACGTGGATGAGAAGAACCAGATGATG ACCACGAACGTATGGGTGAAGCAGCCTCCCCCCGCCCCACCTCATCCAGGAGTGGCACGA CTACAAGCTGCGCTGGGACCCAGCTGACTATGAGAATGTCACCTCCATCCGCATCCCCTC CGAGCTCATCTGGCGGCCGGACATCGTCCTCTACAACAATGCTGACGGGGACTTCGCGGT CACCCACCTGACCAAGGCCCACCTGTTCCATGACGGGCGGGTGCAGTGGACTCCCCCGGC CATTTACAAGAGCTCCTGCAGCATCGACGTCACCTTCTTCCCCTTCGACCAGCAGAACTG CACCATGAAATTCGGCTCCTGGACCTACGACAAGGCCAAGATCGACCTGGTGAACATGCA CAGCCGCGTGGACCAGCTGGACTTCTGGGAGAGTGGCGAGTGGGTCATCGTGGATGCCGT GGGCACCTACAACACCAGGAAGTACGAGTGCTGTGCCGAGATCTACCCGGACATCACCTA TGCCTTCGTCATCCGGCGGCTGCCGCTCTTCTACACCATCAACCTCATCATCCCCTGCCT GCTCATCTCCTGCCTCACCGTGCTGGTCTTCTACCTGCCCTCCGAGTGTGGCGAGAAGAT CACGCTGTGCATCTCCGTGCTGCTGTCGCTCACCGTCTTCCTGCTGCTCATCACCGAGAT CATCCCGTCCACCTCACTGGTCATCCCACTCATCGGCGAGTACCTGCTGTTCACCATGAT CTTCGTCACCCTGTCCATCGTCATCACGGTCTTCGTGCTCAACGTGCACCACCGCTCGCC ACGCACGCACACCATGCCCACCTGGGTACGCAGGGTCTTCCTGGACATCGTGCCACGCCT GCTCCTCATGAAGCGGCCGTCCGTGGTCAAGGACAATTGCCGGCGGCTCATCGAGTCCAT GCATAAGATGGCCAGTGCCCCGCGCTTCTGGCCCGAGCCAGAAGGGGAGCCCCCTGCCAC GAGCGGCACCCAGAGCCTGCACCCGCCCTCACCGTCCTTCTGTGTCCCCCTGGATGTGCC GGCTGAGCCTGGGCCTTCCTGCAAGTCACCCTCCGACCAGCTCCCTCCTCAGCAGCCCCT GGAAGCTGAGAAAGCCAGCCCCCACCCCTCGCCTGGACCCTGCCGCCCGCCCCACGGCAC CCAGGCACCAGGGCTGGCCAAAGCCAGGTCCCTCAGCGTCCAGCACATGTCCAGCCCTGG CGAAGCGGTGGAAGGCGGCGTCCGGTGCCGGTCTCGGAGCATCCAGTACTGTGTTCCCCG AGACGATGCCGCCCCCGAGGCAGATGGCCAGGCTGCCGGCGCCCTGGCCTCTCGCAACAC CCACTCGGCTGAGCTCCCACCCCCAGACCAGCCCTCTCCGTGCAAATGCACATGCAAGAA GGAGCCCTCTTCGGTGTCCCCGAGCGCCACGGTCAAGACCCGCAGCACCAAAGCGCCGCC CCCGCACCTGCCCCTGTCGCCGGCCCTGACCCGGGCGGTGGAGGGCGTCCAGTACATTGC AGACCACCTGAAGGCCGAAGACACAGACTTCTCGGTGAAGGAGGACTGGAAGTACGTGGC CATGGTCATCGACCGCATCTTCCTCTGGATGTTCATCATCGTCTGCCTGCTGGGGACGGT GGGCCTCTTCCTGCCGCCCTGGCTGGCTGGCATGATCTAGGAAGGGACCGGGAGCCTGCG TGGCCTGGGGCTGCCGTGCACGGGGCCAGCATCCATGCGGCCGGCCTGGGGCCGGGCTGG CTTCTCCCTGGACTCTGTGGGGCCACACGTTTGCCAAATTTTCCTTCCTGTTCTGTGTCT GCTGTAAGACGGCCTTGGACGGGGACACGGCCTCTGGGGAGACCGAGTGTGGAGCTGCTT CCAGTTGGACTGTGGCCTCAGGAGGCAGTGGCTTGGAGCAGAGGTGGGGGTCGGCGCCTT CTACCTGCAGGACTCGGGCTAAGTCCAGTTCAAGAGTCTCCTGAGCTCCCCTGCAGATGG AACTCACTCCTCCCAGTCTCTCAGCAGATCTGGTGATGGTCCCGACCGCCCCAAGGGGCC CTTGAAGGGAGTTCACGCCCCTTCAGCCCCAAGCGCCCCGTCTTCTGGAGGCCCGGCCGC CTCTCCCACCCACCGTGTCCTGCGCCTGTGTGGGCTTCAACTTCTCCCCCAGGGTCCTTG AGCCTCTCGGGCCCCATGAGGGTGAGCCAGCAGCGCTCCAATCTGCTTCGCTAGGAGAGG GTCCAGGCAGGGATTGTGTTTGGTTGTGTTTTGGGTAAGTTAGTGAGAACTCAAGTCTTG TGCCTAAGGAGCCTTGGAGAACAGAGTTTTGTGGAGCTGGTTCCGCGTGGGGAGAATCGG GAGGCCCACGCGGGACCAGCTCTCCCCTGCGCAGGCCCTCCGCGGGGGACAGGAACACCC AGCCCCAGCGAGTCTGGAGACCAGGACTCTGCCTTCCAGGCGTAGGGCCAGGGCTCTGGC AGGTGGCCAGGGCTCCACGGGGGCCTAGTGGCTTCAGCCCCTGGGGTACTTCTGTGTTGT GATTCCCCGGAGCTGGGAAGGTCCCGAATGGAGTCCAGACCTGGGCCCTGGTTCCCCCAG GACCCTGAGGGTTTCCACCTTGGCGCGCAGCCCGGGAGATCCGCCCTGGGCTCTGGGTTC GGGAAGAAGGACTTCCTGCTACAGTAGCTGTGGGGAGCTGGTGGGGGCATCCTTGAGGAC CTCCACCTGGGAGATGCTGGGACCCTCGGGGCAGGAAGTCCCTGAGAAGCCTCATGGGAG TCAGGGAGCCCTGGGGTTTCCACACAGGCCCATGCCCTCCGTCCTGGCAGGGCAGGCAGA GCTCAGCACAGCCTCACCCCTGCAGGCGGTATCCAGAGGTGAGGGAGGCCTGAAATGTTT CCAGGCATGACCCTGGAGCCCGGCAGTGCACCCCCTAAAGATGGCGCACCCGGCAGCCCC CCAGTGTCCCCAGGGGCACACTTCCCCTTGGGATGGGCACAGGCTGCCCCACCCCTCCAT GATTCCAAGGGCCCAGAGGGGCGGGGCCAGGATGGCGTGTCCCCTGCCTGTGAGTGACAT CGGTTCAGGAGGAGACAGTCAGGAAGCCTCCTGCTGAGTGGTCCACATTCTGCTGCCCCC AGACCCCATCCAGCCAGGGGTGGGGATGGGGTTGGGCTCTGCGTCCCACTGAGTCTCATT CCTCTGTCCCCGAGCCGAGCTCTCCTGGGCCAGGGTCTCGTCAGGAGGTGCCTGAGAGCA GAATGAATAATTGAGGTTAGGAACCCGGCATGCCGAGTGCCCCAGAAATGCCGCTGTGTC CCCGCGGGCAGTGACGTGAGTGGGGAGGAGACTCAGGCCCACATTGCCCACACCTGCCTC TGAACTGCTGCTGGTCACCCCCACCCCCGGGTGCCTGTGACCGGGGTCCTGAGGCTGGGG CTTTTGTGCCAGGAGTGGGTGGGACACAGAGACCCCCGTGCCAAATCCTGGGCATCCCCA GCCCCCTGGCCCCTCCCACATCCCCCGTGTATTCAGGACCCCATCTGCTGAGCTCTGACC TGCCCCCGCTCTGCCATCAGCCCCTGCTGCTCCTCGGCCAGAGCTCCCAGGACGCAGGGA GACCCTGGGAGAGTGAGGTCATCCCGGGGCCATGGAAGCTGGCAGGAGACACTGGTCTCA GAGGAGGGATAGAGACGCAGATTTCAGATGTAAGAAGCCCGATCCACATTGCATAAGTGG ACCCAGCTGCCAGATGTGTGGGCAGCTGCAGGGAGTGGCCCGGGGTGCTGGGCCCAGCTG TGGTTGTTCTTTTCTGGGTCAGGAGTGACTGCGGAGTGGCTGGGACGCTCCTGCCGGGGG ACCCTCCTGCCGGGGGTGGCCGCTTGCCTGGGGGAAGACCCCTTTCCCTTTCTTTTTTTT TTTGAGGCTCAAAAAAAAAATCCAAATAAAGCACCATATTCCCACCACGCCAAATTAACC TTGACAACAATGTTGGCGTATTTGCGTCCAGTGCTGTTTTTATTAATTAAGGTAAAATTT ACATATGGTGAGATGCATGCTCTTCAGTGGAGACCCAGCCCCTAGAAGGTCCCTCCAGCC CTTCCTGTCGGCGTCCCTCCCCATCTGTGGCTCTGACTTAAGCACCGTGGATTGACCTCT CCGGCTCACGACCTTCGAGGAGTCAGAATCCTGCAGTTGGAGCCTTTGATGTCTGGCTTC TTCATCCTATGACTTAGAGCTTCATCCGTGCTGTTGTGTGTGTCCGTAGCTCCTTGCTGT CTGTTCCTTCGTTTTTAATTGTGAGCAGTGTTCTTCTGTCTGAATAAACTAAGACGCAGT TTGTCCATCACCTGTTAGTGGACTTTGCTTGCAGCTGTCGGTGATTAGGAATGGAGGTGC CGGTGTGTGCATGGCACTCTATCCGTTATGCATGTTTATTTTCTGCATCTGTTAATGTTT TAACATCTTTCAGACCCAGGACTGCTCCTCCTAGGGCCAGTTAGTTCCCGGGGGTGGACA GCTTGCCTAGAACCCACCTTGCCAGGGCTGTGACCCCCGACCCCCTATCAAAGTCTCACA CTAAGCCAACGTTTCCCCGCCCTGTGCCAGGCACCAGGCAGCGGGAGACACTGCTGCAGC TCGAAGCCTGCCGGGGCGCCGGCCCCTCTGCGGCTGCTTGCGCCATCCTGCCCCCTCCTT CCCAGGGGAGGCCCCAGTGAAGGCCCTGGCCAGGGCTTCCCAGCCCCTTCTGCCTCCGGA CCGGCCTGGGTGCTTCCCGTGTGGCCCGGCCTGGGGCGACGTGGCCCTCCTCTCAGGAAG CGTGGTAATCTCTCAATGGCTGGCCTCCGGAGTTGTCACTCAGGCTCCCTTGTAAGTTAA GGCCGGGCCCAGGACACTCTAGGGCACGCAGCTGCTGTGGGACTGCTGGGTTAGGTGTCC CCTGGAGCAGAGGCGGCTTCGGATTTCTAAAGTGGCTGAGTCCTTTCACCTTGCACCAGA AATGCTGGATCAGGCGCAGCACACACAGCACCTGGGGATGCAAGCCCGGCCAGCCCCATG GACCAAGCCCCGCCGACCGTGTGGCCCGCCGAGCCCAGGTGCGGCCGC |
Protein Sequence | >1137 : length: 627 MELGGPGAPRLLPPLLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISD VVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWR PDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG SWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIR RLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTS LVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPTWVRRVFLDIVPRLLLMKR PSVVKDNCRRLIESMHKMASAPRFWPEPEGEPPATSGTQSLHPPSPSFCVPLDVPAEPGP SCKSPSDQLPPQQPLEAEKASPHPSPGPCRPPHGTQAPGLAKARSLSVQHMSSPGEAVEG GVRCRSRSIQYCVPRDDAAPEADGQAAGALASRNTHSAELPPPDQPSPCKCTCKKEPSSV SPSATVKTRSTKAPPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDR IFLWMFIIVCLLGTVGLFLPPWLAGMI |