| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1131 |
Name | CHRM3 |
Synonym | EGBRS|HM3;cholinergic receptor, muscarinic 3;CHRM3;cholinergic receptor, muscarinic 3 |
Definition | acetylcholine receptor, muscarinic 3|m3 muscarinic receptor|muscarinic acetylcholine receptor M3 |
Position | 1q43 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway;PANTHER;P00027 |
Pathway | Pancreatic secretion;KEGG PATHWAY;hsa04972 |
Pathway | Integration of energy metabolism;Reactome;REACT:1505 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway;PANTHER;P00042 |
Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Salivary secretion;KEGG PATHWAY;hsa04970 |
Pathway | Gastric acid secretion;KEGG PATHWAY;hsa04971 |
Pathway | Alzheimer disease-amyloid secretase pathway;PANTHER;P00003 |
Pathway | Regulation of Insulin Secretion by Acetylcholine;PID Reactome;500136 |
Disease | Neuroblastoma;FunDO |
Disease | hypertension;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | IMMUNE;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Asthma;FunDO |
Disease | METABOLIC;GAD |
Disease | asthma and atopy;GAD |
Disease | diabetes, type 2 insulin;GAD |
External Links | |
Links to Entrez Gene | 1131 |
Links to all GeneRIF Items | 1131 |
Links to iHOP | 1131 |
Sequence Information | |
Nucleotide Sequence | >1131 : length: 5683 ATTACACCAGCTCTCTCAGTCCGGGGAGGAGGAGGAGCAGGAGGAACGCGAGGAGGAAGG AGAGGAGGAGCGGCCAGCAGTAGCCACGACCGCCACCACCAGGCAGAGGAAGAGTTCGTG GGGAGGAAAAGACCTCTCCTCCCCCTTGGAGCGCCTTCTCTCTGCTTTTGGAGAAAGGGA ATACACGATAAAGAAGGAGACGGAAAGAAGAGAAAAAGTGAGGCGGGAGACAGAGGGAAA AGGGCGTGAACAGAAAGGGCCGGAGCGTGCAGGGGAGCACAGGGCGCGGGGGCGGCACTG CCGAGCCGGGAGCGCTGCCGCTTGGGCAGGTGCCGCGGCCGCTGCCCGGAGGCGGCATGT GACGCGCGGCCGCAGCTGCCCGCGGGCGGAGCGCTCTCAGACCCCGGAGCGCACACCGCG GGGCCATCGGTGCCATCGCGGATCTCCAGGCTCCTCATCAGTCCGCCGGGGCCGCAGCAG CGCTTCTGGGAAGACGGGCGATGAACTGAAGGGCGGCTCCGGGCAGGGGGGCACGATCTT AAGGACAGTCGCTCCCTGAACGCGGAGCCGGAGGAGACGAAGGGAAGGTGGAGCGGACGC CACCCGCGCACCGGGCAGGCGCGGAGACCGGCGTGGGACAGCCACCTGGAGCGCAGCTGC CAGAAAGAAGGACTTTGCTGCTTTGGGCCAGGATCTGAACTTAGGTGTAAACCATTGCCC TGGCAGAGGGAACCTACCCAGTCCATTGCTGCCTGCTACAAGATATGAACAGTAATGGCA CATATTTTGGTTATGAGTCACTCAGAGGACTGTGGATTGAATGAACTGTATCCATCCCCA TCATGATGTACAGAACCAAGTCTCTTCACTACACTTGTGTTCTGATTAGTGGCCAAATAA ATGACAGTCAGAACTTCAGCTAAGGTACAATAAGGTTTTGCTGTGGCGTGGCACCTGGTC TCTTTCTAGAAGGAAAGTTCAACATACAGCACAATTCTGGACACATTGTATTGGTTTGAT GCTCCTACCTGGAACAGATCCTCATGAGCTAGTAAGTTTGAAGGGGAGTCATAAAGAGGA ACAGGCATTATACGCAAGGCTGAAGAAGCAGTTGGTAACTAACAGTACATCTTTTTCTAA GGAAACATCGGATGAGTAAATATGCTCGATAGGCATACTTGAGTATGACTGCAAAGTGAC TACCTAAGACAGAGAGAGAGAAAAGAGAATGTTCTTCAGCATCAGTGCATCTCTGGTTTC AGTATTATGTGGCAGCCATGTTCTGGAGGAAACCAAGGCCAACACTAAACATAAGTTGCA GAGCTGGCCTGTGGTGGAACTCACAAGTCTTATTGGCAATATATGTGAGGAGACAAAAAG CAACATATGGAGAAATACAAAAATATACTCCCTAGAGATACTGCCTCTTCAGATGTCAAG AAAAACCTGGATGAAATGAAGCAAGAGTGGCACGCTGCAAAGTTACAAATTCAAGGCCAC CCACAGAACCAAACATTAACACTTAGGTGGAGCTGGTCTCTTGGGCAGCCTGACATCTGG TCCACTCCTCTGTCCTATGCCGGGATCATCATGACCGTAGAGATTATGTCACTGTTTTGC ATCCTTGTTACATAACTCAGTTCCTGGTAGATTACTATGTCAGAGAGTCACAATGACCTT GCACAATAACAGTACAACCTCGCCTTTGTTTCCAAACATCAGCTCCTCCTGGATACACAG CCCCTCCGATGCAGGGCTGCCCCCGGGAACCGTCACTCATTTCGGCAGCTACAATGTTTC TCGAGCAGCTGGCAATTTCTCCTCTCCAGACGGTACCACCGATGACCCTCTGGGAGGTCA TACCGTCTGGCAAGTGGTCTTCATCGCTTTCTTAACGGGCATCCTGGCCTTGGTGACCAT CATCGGCAACATCCTGGTAATTGTGTCATTTAAGGTCAACAAGCAGCTGAAGACGGTCAA CAACTACTTCCTCTTAAGCCTGGCCTGTGCCGATCTGATTATCGGGGTCATTTCAATGAA TCTGTTTACGACCTACATCATCATGAATCGATGGGCCTTAGGGAACTTGGCCTGTGACCT CTGGCTTGCCATTGACTACGTAGCCAGCAATGCCTCTGTTATGAATCTTCTGGTCATCAG CTTTGACAGATACTTTTCCATCACGAGGCCGCTCACGTACCGAGCCAAACGAACAACAAA GAGAGCCGGTGTGATGATCGGTCTGGCTTGGGTCATCTCCTTTGTCCTTTGGGCTCCTGC CATCTTGTTCTGGCAATACTTTGTTGGAAAGAGAACTGTGCCTCCGGGAGAGTGCTTCAT TCAGTTCCTCAGTGAGCCCACCATTACTTTTGGCACAGCCATCGCTGCTTTTTATATGCC TGTCACCATTATGACTATTTTATACTGGAGGATCTATAAGGAAACTGAAAAGCGTACCAA AGAGCTTGCTGGCCTGCAAGCCTCTGGGACAGAGGCAGAGACAGAAAACTTTGTCCACCC CACGGGCAGTTCTCGAAGCTGCAGCAGTTACGAACTTCAACAGCAAAGCATGAAACGCTC CAACAGGAGGAAGTATGGCCGCTGCCACTTCTGGTTCACAACCAAGAGCTGGAAACCCAG CTCCGAGCAGATGGACCAAGACCACAGCAGCAGTGACAGTTGGAACAACAATGATGCTGC TGCCTCCCTGGAGAACTCCGCCTCCTCCGACGAGGAGGACATTGGCTCCGAGACGAGAGC CATCTACTCCATCGTGCTCAAGCTTCCGGGTCACAGCACCATCCTCAACTCCACCAAGTT ACCCTCATCGGACAACCTGCAGGTGCCTGAGGAGGAGCTGGGGATGGTGGACTTGGAGAG GAAAGCCGACAAGCTGCAGGCCCAGAAGAGCGTGGACGATGGAGGCAGTTTTCCAAAAAG CTTCTCCAAGCTTCCCATCCAGCTAGAGTCAGCCGTGGACACAGCTAAGACTTCTGACGT CAACTCCTCAGTGGGTAAGAGCACGGCCACTCTACCTCTGTCCTTCAAGGAAGCCACTCT GGCCAAGAGGTTTGCTCTGAAGACCAGAAGTCAGATCACTAAGCGGAAAAGGATGTCCCT GGTCAAGGAGAAGAAAGCGGCCCAGACCCTCAGTGCGATCTTGCTTGCCTTCATCATCAC TTGGACCCCATACAACATCATGGTTCTGGTGAACACCTTTTGTGACAGCTGCATACCCAA AACCTTTTGGAATCTGGGCTACTGGCTGTGCTACATCAACAGCACCGTGAACCCCGTGTG CTATGCTCTGTGCAACAAAACATTCAGAACCACTTTCAAGATGCTGCTGCTGTGCCAGTG TGACAAAAAAAAGAGGCGCAAGCAGCAGTACCAGCAGAGACAGTCGGTCATTTTTCACAA GCGCGCACCCGAGCAGGCCTTGTAGAATGAGGTTGTATCAATAGCAGTGACAAAACGCAC ACATCAACCCACAGACCTTAGGAGGAGGAAGGCGAGGGCGGGGTGACTTCTGGTGATGAT AAAAATGGTTTTATCACCCAGATGTGAAAGAAGCTGCCTGTTTACTGATCCATTGAATAA ACCCATTTTAATAGAAAAAGTCAATACCAATTCAGCAAAAAGAAAAAAAAAACATACTAC TGAATATAAAGAAATTTATTCTGAAATAGACTTTACGTGTTTTTTTCTTAAAGAGGAGAA AAATATTGCTTGACGGCAATTATATACCCAAAGTGATTTGCCTGGGTCCTTTAATTCCCA TTAGCTTTGGAATCTCAGATGAGCATAGCTGACCCAGTTCCCACATTCTTCCCAAGGATC CCAAAAGTGGGAATCCAGACCCCAAGTGGAACACTGCAGGCTTACGAATCTGTGGTTCCA AAATTATTTCATACGTTGCAAAGCTGAATCTTCTTGTCCCAATAGAGCTTCCTGTCTTTT CTTTGGTGTGTTGTTAAACTCTATTTGTGGACTTGATTCTTGATTCTTGCAAAGTACTGT TTTGTGCAGTTCAAGTTTCGTACAAATAAAAATACTTAAGTATATATATATGTGTGAGTT CTGCACGCACACACATAGTGTATATAATATCATGGGAAACACTGAACTGGCAAATTATTC CTGCAACATACGCTTTCAGTACTTTGGTAACTGAAGTTCTCTAGGATCCTAATGCAACAT TAACGTGAAATAAGCCCAGTGTAATGTTTTTGAAACCAGGGCTGTTTTCCACAGAGAGCA GCCAGGCCTTCCCAGCAGGTCTGTGCAGAGCGGACAGGCTCGTGAGTCAGCTGAGCGCCG TGGCTTCGCCAGACTTGGTGTTAAGCAACCTCCTTTGTTGATGTCTCAACAGAGCTAAAT CGGGGCCCCTCTGAGCTCAAAGAATGAACCACATCCACACGTTTGAATTTAATCATCTAA ATCTGAATGTTTCAGAACAAAATTTCTGCTATCTAAACTGCTTGAAACTCAATAATAGTG TCACGTTTGAATGTCATACACAGCAATATATATATATGTGTATATATATATATATGGCAA AGCAAAAAAAAAAACATGGTAAGAGAGAATGAAGGAGAACATTGTGTTTGATTCTTGCTG AATGGCACCTTCTCAAAGAAAATAGGGCTTGCACCTTTGTTAATCAGCTGTGGCCAGTGC TTTCTGGTGTTCATTGTGTAACCTTCACCCAGGAATAGGTGAGGTTTTAGGAAGTTACAT GTCCTCTGAAGAAAGAATTACACTCTGAAAAGTAATGCTTCAAATTGATTTCCTTACCTT TTGGGAAAAAAAAAAAATTGTTTTTTTGCATTCTCCCTTGAATTGACCAAAATGTTAACT GTTTCATTTGGGGAGGGGATGGGGTGCTGCCATCATTGTCGTTGTTGTTGCTGCTGTAGC TGTTGGGGTTTCTTTTCCTGTTGCCGGGGCTGTTTGGGGAGAGGGAGGGGAGGGAGGTGG GAGGGCCGCGGAGATATCTTCCCTTTGTACAGGGCATTCGTGTTGTGAACCCAGAGCTGG GTAGAAGCTGCTTTTGTATTCAGTGTGAGGTGGTGTTTACAGACGACTTTGACAACAGTA GAAGTGTACTCAGTGGTGTCTGTGTATCTGAACTATTTAATTTCGTGTTATGTTTATATG CAGAAATATTTATGGATACTACACCAAGTGTTTATTTAATGTTGATAAATATGACTCTTC AGTCGTCAGCCATGGTGTCCTTTCAAAGTGATTCTTTAAGGTCCACTTGAGCAATGAATA GAGTATATTGGAGCTTTCCTGTGGCTAAGAAGAAGAAACATGTCATCCTGTTGGCATCAC CAAGCACCTAACTCTTTCTAGGTAATAAAAAGTCAACGGTCACTTCAACGTAAATGTTTA AAACCACTCTTTAGTTAAATCTGATGGGAACTGAACAAAGCTCCACCATTGTGTCTGAAA TCATTTTACACAGGGAAAAAAAAAAACAATCAGCATAATTGTAAGAATGATTTTTTTGGG CCCACATTCAACCAAAGAACAAGAAAGAAACAGACGATTTTCTAATATGTACACAGCAAA CTACAGAATGTCATATTATCCACCTGTGAAACATCTAGTAAGCAATTGCATCTATATTTT ATTTCTCAAGTTGGCCTGGCACTAATAAATATGTGAAAGCTTA |
Protein Sequence | >1131 : length: 590 MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPL GGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVI SMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR TTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAF YMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSM KRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSE TRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSF PKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKR MSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVN PVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL |