| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10747 |
Name | MASP2 |
Synonym | MAP19|MASP-2|MASP1P1|sMAP;mannan-binding lectin serine peptidase 2;MASP2;mannan-binding lectin serine peptidase 2 |
Definition | MBL-associated plasma protein of 19 kD|MBL-associated serine protease 2|mannan-binding lectin serine peptidase 1 pseudogene 1|mannan-binding lectin serine protease 1 pseudogene 1|mannan-binding lectin serine protease 2|mannose-binding protein-associated s |
Position | 1p36.3-p36.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Complement and coagulation cascades;KEGG PATHWAY;hsa04610 |
Pathway | lectin induced complement pathway;PID BioCarta;100118 |
Pathway | Staphylococcus aureus infection;KEGG PATHWAY;hsa05150 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Disease | Embryoma;FunDO |
Disease | Mannose-binding lectin pathway component defects;KEGG DISEASE;H00105 |
Disease | Rheumatic fever;FunDO |
Disease | Cystic fibrosis;FunDO |
Disease | Infectious lung disease;FunDO |
Disease | MASP2 deficiency;OMIM |
Disease | Immune system diseases;KEGG DISEASE |
Disease | Neutropenia;FunDO |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | Aortic valve disease;FunDO |
Disease | Enteritis;FunDO |
Disease | Neoplasm metastasis;FunDO |
External Links | |
Links to Entrez Gene | 10747 |
Links to all GeneRIF Items | 10747 |
Links to iHOP | 10747 |
Sequence Information | |
Nucleotide Sequence | >10747 : length: 2471 AGACCAGGCCAGGCCAGCTGGACGGGCACACCATGAGGCTGCTGACCCTCCTGGGCCTTC TGTGTGGCTCGGTGGCCACCCCCTTGGGCCCGAAGTGGCCTGAACCTGTGTTCGGGCGCC TGGCATCCCCCGGCTTTCCAGGGGAGTATGCCAATGACCAGGAGCGGCGCTGGACCCTGA CTGCACCCCCCGGCTACCGCCTGCGCCTCTACTTCACCCACTTCGACCTGGAGCTCTCCC ACCTCTGCGAGTACGACTTCGTCAAGCTGAGCTCGGGGGCCAAGGTGCTGGCCACGCTGT GCGGGCAGGAGAGCACAGACACGGAGCGGGCCCCTGGCAAGGACACTTTCTACTCGCTGG GCTCCAGCCTGGACATTACCTTCCGCTCCGACTACTCCAACGAGAAGCCGTTCACGGGGT TCGAGGCCTTCTATGCAGCCGAGGACATTGACGAGTGCCAGGTGGCCCCGGGAGAGGCGC CCACCTGCGACCACCACTGCCACAACCACCTGGGCGGTTTCTACTGCTCCTGCCGCGCAG GCTACGTCCTGCACCGTAACAAGCGCACCTGCTCAGCCCTGTGCTCCGGCCAGGTCTTCA CCCAGAGGTCTGGGGAGCTCAGCAGCCCTGAATACCCACGGCCGTATCCCAAACTCTCCA GTTGCACTTACAGCATCAGCCTGGAGGAGGGGTTCAGTGTCATTCTGGACTTTGTGGAGT CCTTCGATGTGGAGACACACCCTGAAACCCTGTGTCCCTACGACTTTCTCAAGATTCAAA CAGACAGAGAAGAACATGGCCCATTCTGTGGGAAGACATTGCCCCACAGGATTGAAACAA AAAGCAACACGGTGACCATCACCTTTGTCACAGATGAATCAGGAGACCACACAGGCTGGA AGATCCACTACACGAGCACAGCGCAGCCTTGCCCTTATCCGATGGCGCCACCTAATGGCC ACGTTTCACCTGTGCAAGCCAAATACATCCTGAAAGACAGCTTCTCCATCTTTTGCGAGA CTGGCTATGAGCTTCTGCAAGGTCACTTGCCCCTGAAATCCTTTACTGCAGTTTGTCAGA AAGATGGATCTTGGGACCGGCCAATGCCCGCGTGCAGCATTGTTGACTGTGGCCCTCCTG ATGATCTACCCAGTGGCCGAGTGGAGTACATCACAGGTCCTGGAGTGACCACCTACAAAG CTGTGATTCAGTACAGCTGTGAAGAGACCTTCTACACAATGAAAGTGAATGATGGTAAAT ATGTGTGTGAGGCTGATGGATTCTGGACGAGCTCCAAAGGAGAAAAATCACTCCCAGTCT GTGAGCCTGTTTGTGGACTATCAGCCCGCACAACAGGAGGGCGTATATATGGAGGGCAAA AGGCAAAACCTGGTGATTTTCCTTGGCAAGTCCTGATATTAGGTGGAACCACAGCAGCAG GTGCACTTTTATATGACAACTGGGTCCTAACAGCTGCTCATGCCGTCTATGAGCAAAAAC ATGATGCATCCGCCCTGGACATTCGAATGGGCACCCTGAAAAGACTATCACCTCATTATA CACAAGCCTGGTCTGAAGCTGTTTTTATACATGAAGGTTATACTCATGATGCTGGCTTTG ACAATGACATAGCACTGATTAAATTGAATAACAAAGTTGTAATCAATAGCAACATCACGC CTATTTGTCTGCCAAGAAAAGAAGCTGAATCCTTTATGAGGACAGATGACATTGGAACTG CATCTGGATGGGGATTAACCCAAAGGGGTTTTCTTGCTAGAAATCTAATGTATGTCGACA TACCGATTGTTGACCATCAAAAATGTACTGCTGCATATGAAAAGCCACCCTATCCAAGGG GAAGTGTAACTGCTAACATGCTTTGTGCTGGCTTAGAAAGTGGGGGCAAGGACAGCTGCA GAGGTGACAGCGGAGGGGCACTGGTGTTTCTAGATAGTGAAACAGAGAGGTGGTTTGTGG GAGGAATAGTGTCCTGGGGTTCCATGAATTGTGGGGAAGCAGGTCAGTATGGAGTCTACA CAAAAGTTATTAACTATATTCCCTGGATCGAGAACATAATTAGTGATTTTTAACTTGCGT GTCTGCAGTCAAGGATTCTTCATTTTTAGAAATGCCTGTGAAGACCTTGGCAGCGACGTG GCTCGAGAAGCATTCATCATTACTGTGGACATGGCAGTTGTTGCTCCACCCAAAAAAACA GACTCCAGGTGAGGCTGCTGTCATTTCTCCACTTGCCAGTTTAATTCCAGCCTTACCCAT TGACTCAAGGGGACATAAACCACGAGAGTGACAGTCATCTTTGCCCACCCAGTGTAATGT CACTGCTCAAATTACATTTCATTACCTTAAAAAGCCAGTCTCTTTTCATACTGGCTGTTG GCATTTCTGTAAACTGCCTGTCCATGCTCTTTGTTTTTAAACTTGTTCTTATTGAAAAAA AAAAAAAAAAA |
Protein Sequence | >10747 : length: 686 MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLY FTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSD YSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETL CPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPC PYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPA CSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTS SKGEKSLPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLILGGTTAAGALLYDNWVLT AAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNN KVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTA AYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNC GEAGQYGVYTKVINYIPWIENIISDF |