| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10411 |
Name | RAPGEF3 |
Synonym | CAMP-GEFI|EPAC|EPAC1|HSU79275|bcm910;Rap guanine nucleotide exchange factor (GEF) 3;RAPGEF3;Rap guanine nucleotide exchange factor (GEF) 3 |
Definition | 9330170P05Rik|EPAC 1|Rap1 guanine-nucleotide-exchange factor directly activated by cAMP|cAMP-regulated guanine nucleotide exchange factor I|exchange factor directly activated by cAMP 1|exchange protein directly activated by cAMP 1|rap guanine nucleotide e |
Position | 12q13.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Integration of energy metabolism;Reactome;REACT:1505 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | phospholipase c-epsilon pathway;PID BioCarta;100070 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Disease | Pancreas cancer;FunDO |
Disease | Leukemia;FunDO |
Disease | Heart failure;FunDO |
Disease | smoking behavior;GAD |
Disease | CHEMDEPENDENCY;GAD |
External Links | |
Links to Entrez Gene | 10411 |
Links to all GeneRIF Items | 10411 |
Links to iHOP | 10411 |
Sequence Information | |
Nucleotide Sequence | >10411 : length: 6239 ACTTCGGGGCCGCTCCTGCCCCCTGGGGATACTCTGGGCTCAGGCGGATGTCCACTCTGG TACCCCCGGGTGCGGACTCCAAAGCCTGCCAGTGCCGGCCCCCTTCCCCTACGCATTCCT CTACCGTAAGGCAGGGCGCCTCCACCCCGCCCCCTCCGCCAGTCCTGGGGAGGGGAAGGG GGCGGGCAGCGCAGGGGGTGTGACAGCTCCCGCCCGGACCGGTGCCAGCGCAGCCTTGCT TCAGCGCCCGGTGCCAGCTGGCTCCTTCGTCTGAGACGAAGGCGCAGGCTCGGGGCTCCC TGTCGCCGGTGGCTGGGTGGCGTCCCCCCACCACGCCCCCACCCCTCTACTCACCCAAGA GGAGCCTCTCCACCGAGCCCTGCATCCTGCTGCCCTGGCAGCCAGTCCAGCTAGGCACTG GCCCAGTTCACTGTACCTGGACTTACCCACTGGCACCCTCCGGATCCCCTTATCAAAGCT GATGGGGGTCGCTGGGGACCCCCCAGCCTTTTGCTAGAGCCTGCACGGCTGTGCGAGCTT GAAAAGAAACATGAAGGTGGGCTGGCCAGGTGAGAGCTGCTGGCAGGTGGGCCTGGCTGT GGAGGATAGCCCAGCTCTGGGAGCACCGCGGGTGGGAGCCCTCCCTGACGTGGTGCCGGA GGGGACACTACTCAACATGGTGTTGAGAAGGATGCACCGGCCCCGAAGCTGCTCCTACCA GCTGCTGCTGGAGCACCAGCGTCCGAGCTGCATCCAGGGGCTGCGCTGGACACCACTCAC CAACAGCGAGGAGTCCCTGGATTTCAGCGAGAGCCTGGAGCAGGCCTCCACAGAGCGGGT GCTCAGGGCTGGGAGGCAGCTGCATCGGCATCTGCTGGCCACCTGCCCAAACCTCATCCG AGACCGGAAGTACCACCTTAGGCTCTATCGGCAGTGCTGCTCTGGCCGGGAGCTGGTGGA TGGGATCTTGGCCCTGGGACTTGGGGTCCATTCCCGGAGCCAAGTTGTGGGAATCTGCCA GGTGCTGCTGGATGAAGGTGCCCTCTGCCATGTGAAACACGACTGGGCCTTCCAGGACCG AGATGCCCAATTCTACCGGTTCCCCGGGCCCGAGCCCGAGCCCGTGGGAACTCATGAGAT GGAGGAGGAGTTGGCCGAAGCTGTGGCCCTGCTCTCCCAGCGGGGGCCTGACGCCCTGCT CACTGTGGCACTTCGAAAGCCCCCAGGTCAGCGCACGGATGAAGAGCTGGACCTCATCTT TGAGGAGCTGCTGCACATCAAGGCTGTGGCCCACCTCTCCAACTCGGTGAAGCGAGAATT AGCGGCTGTTCTGCTCTTTGAACCACACAGCAAGGCAGGGACCGTGTTGTTCAGCCAGGG GGACAAGGGCACTTCGTGGTACATTATCTGGAAGGGATCTGTCAACGTGGTGACCCATGG CAAGGGGCTGGTGACCACCCTGCATGAGGGAGATGATTTTGGACAGCTGGCTCTGGTGAA TGATGCACCCCGGGCAGCCACCATCATCCTGCGAGAAGACAACTGTCATTTCCTGCGTGT GGACAAGCAGGACTTCAACCGTATCATCAAGGATGTGGAGGCAAAGACCATGCGGCTGGA AGAACATGGCAAAGTGGTGCTGGTGCTGGAGAGAGCCTCTCAGGGCGCCGGCCCTTCCCG ACCCCCAACCCCAGGCAGGAACCGGTATACAGTGATGTCTGGCACCCCAGAGAAGATCCT AGAGCTTCTGTTGGAGGCCATGGGACCAGATTCCAGTGCTCATGACCCAACAGAGACATT CCTCAGCGACTTCCTCCTGACCCACAGGGTCTTCATGCCCAGCGCCCAACTCTGCGCTGC CCTTCTGCACCACTTCCATGTGGAGCCTGCGGGTGGCAGCGAGCAGGAGCGCAGCACCTA CGTCTGCAACAAGAGGCAGCAGATCTTGCGGCTGGTCAGCCAGTGGGTGGCCCTGTATGG CTCCATGCTCCACACTGACCCTGTGGCCACCAGCTTCCTCCAGAAACTCTCAGACCTGGT GGGCAGGGACACCCGACTCAGCAACCTGCTGAGGGAGCAGTGGCCAGAGAGGCGGCGATG CCACAGGTTGGAGAATGGCTGTGGGAATGCATCTCCTCAGATGAAGGCCCGGAACTTGCC TGTTTGGCTCCCCAACCAGGACGAGCCCCTTCCTGGCAGCAGCTGTGCCATCCAAGTTGG GGATAAAGTCCCCTATGACATCTGCCGGCCAGACCACTCAGTGTTGACCCTGCAGCTGCC TGTGACAGCCTCCGTGAGAGAGGTGATGGCAGCGTTGGCCCAGGAGGATGGCTGGACCAA GGGGCAGGTGCTGGTGAAGGTCAATTCTGCAGGTGATGCCATTGGCCTGCAGCCAGATGC CCGTGGTGTGGCCACATCTCTGGGGCTCAATGAGCGTCTCTTTGTTGTCAACCCACAGGA AGTGCATGAGCTGATCCCACACCCTGACCAGCTGGGGCCCACTGTGGGCTCTGCTGAGGG GCTGGACCTGGTGAGTGCCAAGGACCTGGCAGGCCAGCTGACGGACCACGACTGGAGCCT CTTCAACAGTATCCACCAGGTGGAGCTGATCCACTATGTGCTGGGCCCCCAGCATCTGCG GGATGTCACCACCGCCAACCTGGAGCGCTTCATGCGCCGCTTCAATGAGCTGCAGTACTG GGTGGCCACCGAGCTGTGTCTCTGCCCCGTGCCCGGCCCCCGGGCCCAGCTGCTCAGGAA GTTCATTAAGCTGGCGGCCCACCTCAAGGAGCAGAAGAATCTCAATTCCTTCTTTGCCGT CATGTTTGGCCTCAGCAACTCGGCCATCAGCCGCCTAGCCCACACCTGGGAGCGGCTGCC TCACAAAGTCCGGAAGCTGTACTCCGCCCTCGAGAGGCTGCTGGATCCCTCATGGAACCA CCGGGTATACCGACTGGCCCTCGCCAAGCTCTCCCCTCCTGTCATCCCCTTCATGCCCCT TCTTCTCAAAGACATGACCTTCATTCATGAGGGAAACCACACACTAGTGGAGAATCTCAT CAACTTTGAGAAGATGAGAATGATGGCCAGAGCCGCGCGGATGCTGCACCACTGCCGAAG CCACAACCCTGTGCCTCTCTCACCACTCAGAAGCCGAGTTTCCCACCTCCACGAGGACAG CCAGGTGGCGAGGATTTCCACATGCTCGGAGCAGTCCCTGAGCACCCGGAGTCCAGCCAG CACCTGGGCTTATGTCCAGCAGCTGAAGGTCATTGACAACCAGCGGGAACTCTCCCGCCT CTCCCGAGAGCTGGAGCCATGAGGAGGGGCTGGGACTGGAGCTGGAGCAGGCACTTGCAG CCGGGAAAGCCAGGGTGTGCCGGGCCAAGATACTCACAGGCTGGCCACAGCTGGGCAAGG CTCTCCGTGGAGTGGACTCGAGTCCCTGGAGCAGGCAGTGTGGAGGCAGCCATCCCCTGT GATGACTGGCAGCTAAGGAGGACCTCGGAGTGGACCCGAGCCAGGAATAACGAATGACCC AAGGCCAAGGAAGGGAGGACAGAGAGGCCCCAGGAGTGGGTGGAGAGTGGAGTGCGCTGG GACGTTGTGTGCAATAGAGAGGTCTCCACACCAGATGTCTTCCAGATTCTGTGCCTCTGG CTTTGTTGTCCAGCCAGGCCTGCAGTTTATTTTCACAGTGGACAGAGAGAGAGAGAGAGG CTGCATGTGTGTACCGTGTGTGGCAAGGGCAGGGCCTTGGCCTGGGGCAGGGGCCCCCTG CTTTCTTTCCACAGCTTTCTTCCAACAGCAGGCAGTGGGGCTGCGGGCCTGTGCGGTGGT CCCTGAGGAGCTTTATTGTTACTGTCAACATAGTAGTATGTTCCAGGCCAGCCCAGAGTG GGCGTGGCAGGGAGGCTGAGGCCCCGCCCTCTGGGAAGGAGCTGTGGAGGAGAAGCAGCC CCATGCTGGGCACGGGCCAGACTGGGTCCAAGATCCTGATGCCACCCAGATGTGCCTCCA GGGCTCTGGCCAAAGGGCGGGCTGGAGCCTGGAGCCCCTGTCAGCAGCCAGCCAGGGTGA CCATCAGCTCCCCGTGGTGGTCCAATAGGACTTTACAGTCCAGATGCAACTGACAGCTTC TTCCCAACTGCAATCCCCGCTTTTCCACACTTGAGCTCGTCCTGGCCTGTTGGGCCAGGC TTCTGGGGTCTTCTGGGGGTGGCTTGTGATAGAAACAATGCTGAAGCTTCCGCGGAGAGC CCGTCGCTTGTTGAGGCCCAACAGACTTCCAGGAAATCAGGGTTTATCATCAGTGTTGAG AATGGTCCCAGCAAGCTCTGGTCATACGAAGTCCTCTCTTCCCTGCCCCTTCAGCACTTC CCCTAGGAACCAGCTACTGCCAGGACGCCTCTTGCGAGGCAGAGCTCACCCAGGAAGCTC CAGGGACTCCACCCTCTTGCCTTGCTATTGCCCTGAGTCCTGGCAGCAGGAGGCACTTGT CTGGCCAGAGAGAGAACTCATGGCCCCTGGCATGACTCCTGAGTAGGTATTGAGGCTGCA GGGCCTTGGGCGTCCAGAGGCAGCTGGTATGGCCCCTCTGCACTTCAGCCCCATGGATGT GGATACACAGGCCTGCTGCTTCCAGAAAGGGTCAGAGCCTTTAGCAGGGAGGCAGCACAG CTGGGCTTAGACCTCAGGTCACTAAGTGAATCTGAGCAAGTCAGTGAACAGTTCTCTTCC TTCATTTCTCCACCTGTAAGCCAGGTATGATAAACGCCATACAGCGCTTAGTGACAAACA CATAAAACTGTAGCTCCTGCCTCTGTAGCAGAGGTGACAGCCAAGGGCAGTCCTGTGCTA TCCAGGCCTGGTAGGGGGGCAGCCTCGCCTCAGTTGAGGGCTGAGGGAGAGACTGAGGTG CAGCAGATGGCAGTGGTAACCAAACCAGTTCCCTTGCCGTGGGTGGGGACACAGGAGAAG CACGGAAGCATCTGGAACTGAGCAATCAGGACAGGAGGCTCAAGCCTGGGTGAGTCAGGA GTCCGGGGGCTTTCTTTTCATCCAACCCATTGTCTGCTGGTGTCTCGGCAAAAGCCAGCC AGCCAGCCGTGGCCCTTCACCGTTCTTCAGACTCTAGGGTGAGCCCAGCCCAGCGACACA ACAGAAACCAAGTGCCACGGGGGCCGGTGTCCTCCACCAGCATTTCTCCTCTGGTCACAT CTACGTCCTGATGGGACTTCTCCCTCCTCCTTGGACCATCAGCTTTACAGTCCAGACCAC CCTGCAGCCACCCGGTGGTCTCCCAGCTGCCCCAGTCTCGGGCAGGATGGCTTTTGAGCC TGTTGGGAGAGACCTTGCCAGGAGAATGGTGCCCAGGGCAGGCAAGAGGACACAGACTCT GGGAGCTAGAAGAGTTGCGGCCCAGGGGGCCAGGCCACTCCCAGAGGACAGGAGGCCCAA AAGCGGGGAAAGGCTCCATGTTACGGTGGCCCCATGCTGGGAGTTTGTGCTGCCTTCTGT CTCCCTGACTGCCCAAGCGTGGGGTGGTGTGGGGCAGGAGGCATCCTCTGGTGTTCCCTA GCAGCCCAGGCTGTGTGCAGGGGCTCCCATTTTGTGTCTCAGCTGCAAGAAGGCCACAAA GGGAGGAGGGGCTCATGGGACTGCTGAGAAGAAGGTGTGCAGAAAGGGAGTGTGGCCCTA GATCAGTCCTTTAAAAAGCCTCTGTTACCTGAAAGGAGGTCAAGCAGAGAGGAATGGCTG CGTGTGTGTCCTACCGGGCAGGACAGGACAGAGGGAGGTCATTGTTACACACACATCCCC CCTCCTTTCCTCCTTCCCCTCCACTTCCCTGTGAAGGCCTGAGGCAGGCTGTGGCCAGGC TCAGGCCCTGACTGTGGGGTACACACCAGGGAGGGCCACGCCTCCCCACAGACGGGGTGG AGTGGTCAGTGGAGCCAGCACCCTCTGCTGCTTCAGCATCTCCGCCTGGAGCCAGCTGTC CCCTCTCTCTCAGGCTCCATCCGAACAAAAGGAAGGCAGAGCCTGAGATCCGGCACCCCA TCCCCCTCCACTCAGCACTGAGTTAGAGCTGGGTGGGGGCATGTCTGCCTTCACACGCTG CCTTATGGCTTCTGTGTCTCCAACAGCCCTCAGCCTCTGGCTGCTCTCCTTCCCAATAGT CACAAGATTTACCATGATAATAATAGGTTAAGACTTGAAAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >10411 : length: 950 MAQREEIKRPLWETVGWPGESCWQVGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRM HRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHL LATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHA SISSPPPRLGLCPPVKHDWAFQDRDAQFYRFPGPEPEPVRTHEMEEELAEAVALLSQRGP DALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVL FSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCH FLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTP EKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQE RSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPE RRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLT LQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVV NPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGP QHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNS FFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIP FMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHL HEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP |