| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10395 |
Name | DLC1 |
Synonym | ARHGAP7|HP|STARD12|p122-RhoGAP;DLC1 Rho GTPase activating protein;DLC1;DLC1 Rho GTPase activating protein |
Definition | Rho-GTPase-activating protein 7|START domain-containing protein 12|StAR-related lipid transfer (START) domain containing 12|deleted in liver cancer 1 protein|deleted in liver cancer 1 variant 2|rho GTPase-activating protein 7|rho-type GTPase-activating pr |
Position | 8p22 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling by Rho GTPases;Reactome;REACT:11044 |
Pathway | phospholipase c delta in phospholipid associated cell signaling;PID BioCarta;100071 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Regulation of RhoA activity;PID Curated;200050 |
Disease | Cancer;FunDO |
Disease | Colorectal cancer, somatic;OMIM |
External Links | |
Links to Entrez Gene | 10395 |
Links to all GeneRIF Items | 10395 |
Links to iHOP | 10395 |
Sequence Information | |
Nucleotide Sequence | >10395 : length: 7479 TCCTCAGAGGCAGGAAATACTTTCCAGGCAATCTGGGCCTGGTTGTGGAGGCCCCTTTTG CAAAACCTCAGTCTGAATTTAGTAGACAGAAGTCACTAGGAATGCCTTGACAGGATCCTG CCTTAGCTAAGGCTCCCTCCAGCTGCAGAGGGTGTTTTTGTTAGACTCACACACTGCGTG AAACTGCTCAGAATAGAGCCATGATCTCAACCACGAAATGGGAACTTAGATTTTGGAGAA ACTAACGGGGACGGACTTCTTTCCTAGCCTGAGTGTTGAGCAGTGTCATGCCTTGGCGTT TCAGCTCCTCGTTGTCTAGGTGGTGAAATGACAGAACTCATTCGCTTCTTTGATTGGTGA TTTTGAAATAATCTTTCATCAAGTTCCATCTCCTTTACCCTCATATGGAATATATCTCTC TGTCTGTTGTTAAACTACGATGACATGTCTGTAGCTATCAGAAAGAGAAGCTGGGAAGAA CATGTGACCCACTGGATGGGACAGCCTTTTAATTCTGATGATCGTAACACAGCATGTCAT CATGGACTAGTAGCTGACAGCTTGCAGGCAAGTATGGAAAAAGATGCAACTCTAAATGTG GACCGCAAAGAGAAGTGTGTTTCACTACCTGACTGCTGTCATGGATCAGAGCTGAGAGAT TTTCCTGGGAGGCCAATGGGTCATCTTTCAAAGGATGTGGACGAAAATGACAGCCATGAA GGTGAAGATCAGTTTCTTTCTCTGGAAGCCAGCACAGAAACACTAGTGCATGTTTCTGAT GAGGATAACAATGCTGATTTATGCCTTACAGATGATAAACAGGTTTTAAATACCCAAGGG CAGAAAACATCAGGCCAACATATGATCCAAGGAGCAGGCTCCTTAGAAAAGGCACTGCCC ATCATACAAAGTAACCAAGTTTCTTCTAACTCCTGGGGAATAGCTGGTGAAACTGAATTA GCACTGGTAAAAGAAAGTGGGGAGAGAAAAGTTACTGACTCTATAAGTAAAAGCCTGGAG CTTTGCAATGAAATAAGCTTAAGTGAAATAAAAGATGCACCCAAAGTAAATGCAGTGGAT ACTTTGAACGTGAAAGATATTGCACCTGAGAAACAATTGCTTAACTCTGCTGTAATTGCT CAGCAACGAAGGAAACCTGACCCCCCTAAAGATGAAAATGAAAGAAGCACCTGCAATGTA GTACAAAATGAGTTCTTGGATACTCCTTGCACAAACAGAGGACTGCCATTATTAAAAACA GATTTTGGAAGCTGCCTTCTGCAGCCTCCTTCCTGCCCCAATGGAATGTCAGCTGAAAAT GGCCTGGAGAAGAGTGGTTTTTCACAACATCAAAACAAAAGTCCACCAAAGGTCAAGGCA GAAGATGGCATGCAGTGTTTACAATTAAAGGAGACCCTGGCCACCCAGGAACCCACAGAT AACCAAGTCAGACTTCGTAAGAGAAAGGAAATAAGAGAAGATCGAGATAGGGCGCGGCTG GACTCCATGGTGCTGCTGATTATGAAACTGGACCAGCTTGATCAGGACATAGAAAATGCC CTCAGCACCAGCTCCTCTCCATCAGGCACACCAACAAACCTGCGGCGGCACGTTCCTGAT CTGGAATCAGGATCTGAAAGTGGAGCAGATACCATTTCAGTAAATCAGACACGAGTAAAT TTGTCTTCTGACACTGAGTCCACGGACCTCCCATCTTCCACTCCAGTAGCCAATTCTGGA ACCAAACCCAAGACTACGGCTATTCAAGGTATTTCAGAGAAGGAAAAGGCTGAAATTGAA GCCAAGGAAGCTTGTGATTGGCTACGGGCAACTGGTTTCCCCCAGTATGCACAGCTTTAT GAAGATTTCCTGTTCCCCATCGATATTTCCTTGGTCAAGAGAGAGCATGATTTTTTGGAC AGAGATGCCATTGAGGCTCTATGCAGGCGTCTAAATACTTTAAACAAATGTGCGGTGATG AAGCTAGAAATTAGTCCTCATCGGAAACGAAGTGACGATTCAGACGAGGATGAGCCTTGT GCCATCAGTGGCAAATGGACTTTCCAAAGGGACAGCAAGAGGTGGTCCCGGCTTGAAGAG TTTGATGTCTTTTCTCCAAAACAAGACCTGGTCCCTGGGTCCCCAGACGACTCCCACCCG AAGGACGGCCCCAGCCCCGGAGGCACGCTGATGGACCTCAGCGAGCGCCAGGAGGTGTCT TCCGTCCGCAGCCTCAGCAGCACTGGCAGCCTCCCCAGCCACGCGCCCCCCAGCGAGGAT GCTGCCACCCCCCGGACTAACTCCGTCATCAGCGTTTGCTCCTCCAGCAACTTGGCAGGC AATGACGACTCTTTCGGCAGCCTGCCCTCTCCCAAGGAACTGTCCAGCTTCAGCTTCAGC ATGAAAGGCCACGAAAAAACTGCCAAGTCCAAGACGCGCAGTCTGCTGAAACGGATGGAG AGCCTGAAGCTCAAGAGCTCCCATCACAGCAAGCACAAAGCGCCCTCAAAGCTGGGGTTG ATCATCAGCGGGCCCATCTTGCAAGAGGGGATGGATGAGGAGAAGCTGAAGCAGCTCAAC TGCGTGGAGATCTCCGCCCTCAATGGCAACCGCATCAACGTCCCCATGGTACGAAAGAGG AGCGTTTCCAACTCCACGCAGACCAGCAGCAGCAGCAGCCAGTCGGAGACCAGCAGCGCG GTCAGCACGCCCAGCCCTGTTACGAGGACCCGGAGCCTCAGTGCGTGCAACAAGCGGGTG GGCATGTACTTAGAGGGCTTCGATCCTTTCAATCAGTCAACATTTAACAACGTGGTGGAG CAGAACTTTAAGAACCGCGAGAGCTACCCAGAGGACACGGTGTTCTACATCCCTGAAGAT CACAAGCCTGGCACTTTCCCCAAAGCTCTCACCAATGGCAGTTTCTCCCCCTCGGGGAAT AACGGCTCTGTGAACTGGAGGACGGGAAGCTTCCACGGCCCTGGCCACATCAGCCTCAGG AGGGAAAACAGTAGCGACAGCCCCAAGGAACTGAAGAGACGCAATTCTTCCAGCTCCATG AGCAGCCGCCTGAGCATCTACGACAACGTGCCGGGCTCCATCCTCTACTCCAGTTCAGGG GACCTGGCGGATCTGGAGAACGAGGACATCTTCCCCGAGCTGGACGACATCCTCTACCAC GTGAAGGGGATGCAGCGGATAGTCAATCAGTGGTCGGAGAAGTTTTCTGATGAGGGAGAT TCGGACTCAGCCCTGGACTCGGTCTCTCCCTGCCCGTCCTCTCCAAAACAGATACACCTG GATGTGGACAACGACCGAACCACACCCAGCGACCTGGACAGCACAGGCAACTCCCTGAAT GAACCGGAAGAGCCCTCCGAGATCCCGGAAAGAAGGGATTCTGGGGTTGGGGCTTCCCTA ACCAGGTCCAACAGGCACCGACTGAGATGGCACAGTTTCCAGAGCTCACATCGGCCAAGC CTCAACTCTGTATCACTACAGATTAACTGCCAGTCTGTGGCCCAGATGAACCTGCTGCAG AAATACTCACTCCTAAAGCTAACGGCCCTGCTGGAGAAATACACACCTTCTAACAAGCAT GGTTTTAGCTGGGCCGTGCCCAAGTTCATGAAGAGGATCAAGGTTCCAGACTACAAGGAC CGGAGTGTGTTTGGGGTCCCACTGACGGTCAACGTGCAGCGCACAGGACAACCGTTGCCT CAGAGCATCCAGCAGGCCATGCGATACCTCCGGAACCATTGTTTGGATCAGGTTGGGCTC TTCAGAAAATCGGGGGTCAAGTCCCGGATTCAGGCTCTGCGCCAGATGAATGAAGGTGCC ATAGACTGTGTCAACTACGAAGGACAGTCTGCTTATGACGTGGCAGACATGCTGAAGCAG TATTTTCGAGATCTTCCTGAGCCACTAATGACGAACAAACTCTCGGAAACCTTTCTACAG ATCTACCAATATGTGCCCAAGGACCAGCGCCTGCAGGCCATCAAGGCTGCCATCATGCTG CTGCCTGACGAGAACCGGGAGGTTCTGCAGACCCTGCTTTATTTCCTGAGCGATGTCACA GCAGCCGTAAAAGAAAACCAGATGACCCCAACCAACCTGGCCGTGTGCTTAGCGCCTTCC CTCTTCCATCTCAACACCCTGAAGAGAGAGAATTCCTCTCCCAGGGTAATGCAAAGAAAA CAAAGTTTGGGCAAACCAGATCAGAAAGATTTGAATGAAAACCTAGCTGCCACTCAAGGG CTGGCCCATATGATCGCCGAGTGCAAGAAGCTTTTCCAGGTTCCCGAGGAAATGAGCCGA TGTCGTAATTCCTATACCGAACAAGAGCTGAAGCCCCTCACTCTGGAAGCACTCGGGCAC CTGGGTAATGATGACTCAGCTGACTACCAACACTTCCTCCAGGACTGTGTGGATGGCCTG TTTAAAGAAGTCAAAGAGAAGTTTAAAGGCTGGGTCAGCTACTCCACTTCGGAGCAGGCT GAGCTGTCCTATAAGAAGGTGAGCGAAGGACCCCCTCTGAGGCTTTGGAGGTCAGTCATT GAAGTCCCTGCTGTGCCAGAGGAAATCTTAAAGCGCCTACTTAAAGAACAGCACCTCTGG GATGTAGACCTGTTGGATTCAAAAGTGATCGAAATTCTGGACAGCCAAACTGAAATTTAC CAGTATGTCCAAAACAGTATGGCACCTCATCCTGCTCGAGACTACGTTGTTTTAAGAACC TGGAGGACTAATTTACCCAAAGGAGCCTGTGCCCTTTTACTAACCTCTGTGGATCACGAT CGCGCACCTGTGGTGGGTGTGAGGGTTAATGTGCTCTTGTCCAGGTATTTGATTGAACCC TGTGGGCCAGGAAAATCCAAACTCACCTACATGTGCAGAGTTGACTTAAGGGGCCACATG CCAGAATGGTACACAAAATCTTTTGGACATTTGTGTGCAGCTGAAGTTGTAAAGATCCGG GATTCCTTCAGTAACCAGAACACTGAAACCAAAGACACCAAATCTAGGTGATCACTGAAG CAACGCAACCGCTTCCACCACCATGGTGTTTGTTTCTAGAACTTTTGCCAGTCCTTGAAG AATGGGTTCTGTGTCTAATCCTGAAACAAAGAAAACTACAAGCTGGAGTGTAGGAATTGA CTATAGCAATTTGATACATTTTTAAAGCTGCTTCCTGTTTGTTGAGGGTCTGTATTCATA GACCTTGACTGGAATATGTAAGACTGTGCAAAAAAAAAAAAAAAATTTATGTGTATTCTT ATTCAAATTGCTTCTGAGAAGCAAAACTCTTTAAATACATTATGGAAGATAATGAAGATA CTTCATTCTCTTGTGATATCAGTGTATGCGTACCTGTGTCGCTTTATTTGCAGTGTGTTG AGGGACTGGTGTATCCACTGGAATAGTTGGTACTCTTGGATGTGTTTTCTCACCAAGATG AGCAAAGAAAGGTTTGCACAGAGGAGTGTGAATGTGTGTTTGTTGCTGGCTGAATGGCAA TAGATGTCTAAGGTGGATTCAGTGTCTGGCACACTGAGACACCTCCAAGAAGGAGATTGA TGCATCAGGTTCAGTTTAACCTGGAATATCTGACTACCCCTGAATCCACCCAGAAAGGGG GCCCAACACCCTTGTCCATTTATGGGTATTTTTTTTCGAAGTTATTAAGCATATTCCTTT TCCACGAACCTCTTCTGTACTTTGATTGTAATAGGTTGGCTCTTACACCCATTCCAAATG CAGTTTATTTTTAGACCCGATTGCAAATAGTGATGTAGTTTTAACCAGTATGGATTAGTT CAGGGATGAACTGCTCCCTCTAGCCTTACTGGCTCTGATCCACAGGGTTTTGTTTTGTTT TGTTTTGTTTTTTGTTTAAGTCGAGATATAAAAACTGAACACGATAACACTTACTCTTAA ATCAAGCATCAACACTTTTTCCCTGTTAGAATTCTTTGCATTTTTGTGTTTGTAACAGAA ACGCCTTAAGACACTATGTTTGGGAATATAGGAAACTATGTGTGTCCCAAGGAAATCCCT GTAAATTTAACTCACCTACAAAAGGCTTTTTCCCCGCCTTTGGTTGTTAACGGCATTCCT GAAAGCCACATGTGTTTATTCATTGGGCTTGTTCTTATCAGCAAATAGGTTTTCTGGTTT TATGACTTTTTGTCTTATTTTATTTTTCCTACATTTCTTTTTTTTTTTTTTTCCTTTAGA ATGCCCTGGAAATATATTTAAGTGGTAATGAAAAATAGTAATCATAGTAAAACGCAACAA GAAGAAAACCAACCCAAACCAGTGAAGTTTTTTAGAACCTTTAGAAGGGTGGTCTTTATT CAGGTTTTACTGTAATGGTAAGGATTGACTCAAGAGACAGTATTAGTAAATTTATTGTGT ATGGATCAAAAGTGAATAATGTATGAATGAGAGCTGTAAGAAGGATTTTTATTTTGTTAT AATTTAGTTACCATTTTCAGTGTTATTTCAAAGGTTCTTTGAAGAATTTTGGGGCAGGGC ATCAGATTAGAGTTTTAAAATTTGAGTATTTTGGATATCAGTGTTCCTCATGAAGATATA CATGGATATTCAATTTTGATGGCTTCCAGATTTGTAAGATTGTATGTTGTATATACCATT CTATTAAGAAACATGTCCACTGTGCTTTCAAACATAGATAAAGCATGATAAAGATTATTA TTTAAGATATACTTGTATTTATACCTCAGATATTCTTTTGGGTTTTGTACCTCAAGGCTT TTTTCTTCTTATTGTAAATACACTTTACGTGAATACAGTCTAAGTGAAGAAAATAAATAA AAGGAAGAGGTTTATAACTTGCTCTATATCTGTACAGATTATAATCAATAAGTGCACTAT TATTAAATGTTTAAAGTAAGGGAAAAGTCTGGGCTGCCTTCCTTAATATTGCATCTCACT CCCACCCTTAAAACCACAGATTGCAAAGCATAGCATTTTAGCATCAACTACAATCAAAAG AGCGATTTGCTGAAGGAAAAATCGGACTGCAAATCATTCCAAGGCCAAACTGCAACTGAG CCACCCACTCCCAAACAGGAAACCCTGGTGAAGGTTCAGGAAGCACGGAGATTCTCTCCA ACAAAGGTCCAGTTAGGAAACGACGCTGAGAGGATGACGACAACGTGCAACAGCAGAAAG ATGCTTGCAAGCAGAGTCAGGGTCACCAGTGAATGCCACAAAAGTTCTCTTTCCCACTGT TTAATTTGACAAGAGAAGAATTTGAAGGATATGAACATTTTCAAGAACTCTGCTGAGGTC ACTTAGAGCGCCATCACAACTTATTTGTGTGACTAATTGCCTAGATTGTAAGCTCTTTGA GGGCAGGGCTTGTCTCTTACACATCTTTATAATCCCCTGCAGCGGCTTTCAGTATTTTGT ACTTGTAGGCACCTAATAAATTTATTATTTGCTATACTG |
Protein Sequence | >10395 : length: 1528 MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP PKDENERSTCNVVQNEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF GHLCAAEVVKIRDSFSNQNTETKDTKSR |