| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10320 |
Name | IKZF1 |
Synonym | Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1;IKAROS family zinc finger 1 (Ikaros);IKZF1;IKAROS family zinc finger 1 (Ikaros) |
Definition | CLL-associated antigen KW-6|DNA-binding protein Ikaros|ikaros family zinc finger protein 1|lymphoid transcription factor LyF-1|protein phosphatase 1, regulatory subunit 92|zinc finger protein, subfamily 1A, 1 (Ikaros) |
Position | 7p12.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Disease | Leukemia, acute lymphoblastic;OMIM |
Disease | hippocampal atrophy;GAD |
Disease | Bone marrow disease;FunDO |
Disease | Hippocampal atrophy;NHGRI |
Disease | Mean corpuscular volume;NHGRI |
Disease | HEMATOLOGICAL;GAD |
Disease | Acute lymphoblastic leukemia (childhood);NHGRI |
Disease | Acute lymphoblastic leukemia (childhood);GAD |
Disease | IMMUNE;GAD |
Disease | Lymphoma;FunDO |
Disease | Leukemia;FunDO |
Disease | CANCER;GAD |
Disease | Lymphoproliferative disorder;FunDO |
Disease | Systemic lupus erythematosus;NHGRI |
Disease | Hematopoietic system disease;FunDO |
Disease | systemic lupus erythematosus;GAD |
Disease | mean corpuscular volume;GAD |
Disease | NEUROLOGICAL;GAD |
External Links | |
Links to Entrez Gene | 10320 |
Links to all GeneRIF Items | 10320 |
Links to iHOP | 10320 |
Sequence Information | |
Nucleotide Sequence | >10320 : length: 6459 CGCGGGGCAGCCGGTCGGCCGGGAGCGCGAAAGCCTGGTCTGAGCCGGCTGGGGGCGGGG AGTGTGGCGGAGAAATGGGGAACAATGCGAGTGAGCAACTTCAGGAAGTCATTGTGAAAG AAAGCTGGGAAGAGCTCCGCGGCCAAGTTAGCAGGACACTCTAACAAGTGACTGCGCGGC CCGCGCCCGGGGCGGTGACTGCGGCAAGCCCCCTGGGTCCCCGCGCGGCGCATCCCAGCC TGGGCGGGACGCTCGGCCGCGGCGAGGCGGGCAAGCCTGGCAGGGCAGAGGGAGCCCCGG CTCCGAGGTTGCTCTTCGCACCCGAGGATCAGTCTTGGCCCCAAAGCGCGACGCACAAAT CCACATAACCTGAGGACCATGGATGCTGATGAGGGTCAAGACATGTCCCAAGTTTCAGGG AAGGAAAGCCCCCCTGTAAGCGATACTCCAGATGAGGGCGATGAGCCCATGCCGATCCCC GAGGACCTCTCCACCACCTCGGGAGGACAGCAAAGCTCCAAGAGTGACAGAGTCGTGGTT ACATATGGGGCTGATGACTTTAGGGATTTCCATGCAATAATTCCCAAATCTTTCTCTCCC AGTAATGTTAAAGTAGAGACTCAGAGTGATGAAGAGAATGGGCGTGCCTGTGAAATGAAT GGGGAAGAATGTGCGGAGGATTTACGAATGCTTGATGCCTCGGGAGAGAAAATGAATGGC TCCCACAGGGACCAAGGCAGCTCGGCTTTGTCGGGAGTTGGAGGCATTCGACTTCCTAAC GGAAAACTAAAGTGTGATATCTGTGGGATCATTTGCATCGGGCCCAATGTGCTCATGGTT CACAAAAGAAGCCACACTGGAGAACGGCCCTTCCAGTGCAATCAGTGCGGGGCCTCATTC ACCCAGAAGGGCAACCTGCTCCGGCACATCAAGCTGCATTCCGGGGAGAAGCCCTTCAAA TGCCACCTCTGCAACTACGCCTGCCGCCGGAGGGACGCCCTCACTGGCCACCTGAGGACG CACTCCGTTGGTAAACCTCACAAATGTGGATATTGTGGCCGAAGCTATAAACAGCGAAGC TCTTTAGAGGAACATAAAGAGCGCTGCCACAACTACTTGGAAAGCATGGGCCTTCCGGGC ACACTGTACCCAGTCATTAAAGAAGAAACTAATCACAGTGAAATGGCAGAAGACCTGTGC AAGATAGGATCAGAGAGATCTCTCGTGCTGGACAGACTAGCAAGTAACGTCGCCAAACGT AAGAGCTCTATGCCTCAGAAATTTCTTGGGGACAAGGGCCTGTCCGACACGCCCTACGAC AGCAGCGCCAGCTACGAGAAGGAGAACGAAATGATGAAGTCCCACGTGATGGACCAAGCC ATCAACAACGCCATCAACTACCTGGGGGCCGAGTCCCTGCGCCCGCTGGTGCAGACGCCC CCGGGCGGTTCCGAGGTGGTCCCGGTCATCAGCCCGATGTACCAGCTGCACAAGCCGCTC GCGGAGGGCACCCCGCGCTCCAACCACTCGGCCCAGGACAGCGCCGTGGAGAACCTGCTG CTGCTCTCCAAGGCCAAGTTGGTGCCCTCGGAGCGCGAGGCGTCCCCGAGCAACAGCTGC CAAGACTCCACGGACACCGAGAGCAACAACGAGGAGCAGCGCAGCGGTCTCATCTACCTG ACCAACCACATCGCCCCGCACGCGCGCAACGGGCTGTCGCTCAAGGAGGAGCACCGCGCC TACGACCTGCTGCGCGCCGCCTCCGAGAACTCGCAGGACGCGCTCCGCGTGGTCAGCACC AGCGGGGAGCAGATGAAGGTGTACAAGTGCGAACACTGCCGGGTGCTCTTCCTGGATCAC GTCATGTACACCATCCACATGGGCTGCCACGGCTTCCGTGATCCTTTTGAGTGCAACATG TGCGGCTACCACAGCCAGGACCGGTACGAGTTCTCGTCGCACATAACGCGAGGGGAGCAC CGCTTCCACATGAGCTAAAGCCCTCCCGCGCCCCCACCCCAGACCCCGAGCCACCCCAGG AAAAGCACAAGGACTGCCGCCTTCTCGCTCCCGCCAGCAGCATAGACTGGACTGGACCAG ACAATGTTGTGTTTGGATTTGTAACTGTTTTTTGTTTTTTGTTTGAGTTGGTTGATTGGG GTTTGATTTGCTTTTGAAAAGATTTTTATTTTTAGAGGCAGGGCTGCATTGGGAGCATCC AGAACTGCTACCTTCCTAGATGTTTCCCCAGACCGCTGGCTGAGATTCCCTCACCTGTCG CTTCCTAGAATCCCCTTCTCCAAACGATTAGTCTAAATTTTCAGAGAGAAATAGATAAAA CACGCCACAGCCTGGGAAGGAGCGTGCTCTACCCTGTGCTAAGCACGGGGTTCGCGCACC AGGTGTCTTTTTCCAGTCCCCAGAAGCAGAGAGCACAGCCCCTGCTGTGTGGGTCTGCAG GTGAGCAGACAGGACAGGTGTGCCGCCACCCAAGTGCCAAGACACAGCAGGGCCAACAAC CTGTGCCCAGGCCAGCTTCGAGCTACATGCATCTAGGGCGGAGAGGCTGCACTTGTGAGA GAAAATACTATTTCAAGTCATATTCTGCGTAGGAAAATGAATTGGTTGGGGAAAGTCGTG TCTGTCAGACTGCCCTGGGTGGAGGGAGACGCCGGGCTAGAGCCTTTGGGATCGTCCTGG ATTCACTGGCTTTGCGGAGGCTGCTCAGATGGCCTGAGCCTCCCGAGGCTTGCTGCCCCG TAGGAGGAGACTGTCTTCCCGTGGGCATATCTGGGGAGCCCTGTTCCCCGCTTTTTCACT CCCATACCTTTAATGGCCCCCAAAATCTGTCACTACAATTTAAACACCAGTCCCGAAATT TGGATCTTCTTTCTTTTTGAATCTCTCAAACGGCAACATTCCTCAGAAACCAAAGCTTTA TTTCAAATCTCTTCCTTCCCTGGCTGGTTCCATCTAGTACCAGAGGCCTCTTTTCCTGAA GAAATCCAATCCTAGCCCTCATTTTAATTATGTACATCTGTTTGTAGCCACAAGCCTGAA TTTCTCAGTGTTGGTAAGTTTCTTTACCTACCCTCACTATATATTATTCTCGTTTTAAAA CCCATAAAGGAGTGATTTAGAACAGTCATTAATTTTCAACTCAATGAAATATGTGAAGCC CAGCATCTCTGTTGCTAACACACAGAGCTCACCTGTTTGAAACCAAGCTTTCAAACATGT TGAAGCTCTTTACTGTAAAGGCAAGCCAGCATGTGTGTCCACACATACATAGGATGGCTG GCTCTGCACCTGTAGGATATTGGAATGCACAGGGCAATTGAGGGACTGAGCCAGACCTTC GGAGAGTAATGCCACCAGATCCCCTAGGAAAGAGGAGGCAAATGGCACTGCAGGTGAGAA CCCCGCCCATCCGTGCTATGACATGGAGGCACTGAAGCCCGAGGAAGGTGTGTGGAGATT CTAATCCCAACAAGCAAGGGTCTCCTTCAAGATTAATGCTATCAATCATTAAGGTCATTA CTCTCAACCACCTAGGCAATGAAGAATATACCATTTCAAATATTTACAGTACTTGTCTTC ACCAACACTGTCCCAAGGTGAAATGAAGCAACAGAGAGGAAATTGTACATAAGTACCTCA GCATTTAATCCAAACAGGGGTTCTTAGTCTCAGCACTATGACATTTTGGGCTGACTACTT ATTTGTTAGGCGGGAGCTCTCCTGTGCATTGTAGGATAATTAGCAGTATCCCTGGTGGCT ACCCAATAGACGCCAGTAGCACCCCGAATTGACAACCCAAACTCTCCAGACATCACCAAC TGTCCCCTGCGAGGAGAAATCACTCCTGGGGGAGAACCACTGACCCAAATGAATTCTAAA CCAATCAAATGTCTGGGAAGCCCTCCAAGAAAAAAAATAGAAAAGCACTTGAAGAATATT CCCAATATTCCCGGTCAGCAGTATCAAGGCTGACTTGTGTTCATGTGGAGTCATTATAAA TTCTATAAATCAATTATTCCCCTTCGGTCTTAAAAATATATTTCCTCATAAACATTTGAG TTTTGTTGAAAAGATGGAGTTTACAAAGATACCATTCTTGAGTCATGGATTTCTCTGCTC ACAGAAGGGTGTGGCATTTGGAAACGGGAATAAACAAAATTGCTGCACCAATGCACTGAG TGAAGGAAGAGAGACAGAGGATCAAGGGCTTTAGACAGCACTCCTTCAATATGCAATCAC AGAGAAAGATGCGCCTTATCCAAGTTAATATCTCTAAGGTGAGAGCCTTCTTAGAGTCAG TTTGTTGCAAATTTCACCTACTCTGTTCTTTTCCATCCATCCCCCTGAGTCAGTTGGTTG AAGGGAGTTATTTTTTCAAGTGGAATTCAAACAAAGCTCAAACCAGAACTGTAAATAGTG ATTGCAGGAATTCTTTTCTAAACTGCTTTGCCCTTTCCTCTCACTGCCTTTTATAGCCAA TATAAATGTCTCTTTGCACACCTTTTGTTGTGGTTTTATATTGTAACACCATTTTTCTTT GAAACTATTGTATTTAAAGTAAGGTTTCATATTATGTCAGCAAGTAATTAACTTATGTTT AAAAGGTGGCCATATCATGTACCAAAAGTTGCTGAAGTTTCTCTTCTAGCTGGTAAAGTA GGAGTTTGCATGACTTCACACTTTTTTTGCGTAGTTTCTTCTGTTGTATGATGGCGTGAG TGTGTGTCTTGGGTACCGCTGTGTACTACTGTGTGCCTAGATTCCATGCACTCTCGTTGT GTTTGAAGTAAATATTGGAGACCGGAGGGTAACAGGTTGGCCTGTTGATTACAGCTAGTA ATCGCTGTGTCTTGTTCCGCCCCCTCCCTGACACCCCAGCTTCCCAGGATGTGGAAAGCC TGGATCTCAGCTCCTTGCCCCATATCCCTTCTGTAATTTGTACCTAAAGAGTGTGATTAT CCTAATTCAAGAGTCACTAAAACTCATCACATTATCATTGCATATCAGCAAAGGGTAAAG TCCTAGCACCAATTGCTTCACATACCAGCATGTTCCATTTCCAATTTAGAATTAGCCACA TAATAAAATCTTAGAATCTTCCTTGAGAAAGAGCTGCCTGAGATGTAGTTTTGTTATATG GTTCCCCACCGACCATTTTTGTGCTTTTTTCTTGTTTTGTTTTGTTTTGACTGCACTGTG AGTTTTGTAGTGTCCTCTTCTTGCCAAAACAAACGCGAGATGAACTGGACTTATGTAGAC AAATCGTGATGCCAGTGTATCCTTCCTTTCTTCAGTTCCAGCAATAATGAATGGTCAACT TTTTTAAAATCTAGATCTCTCTCATTCATTTCAATGTATTTTTACTTTAAGATGAACCAA AATTATTAGACTTATTTAAGATGTACAGGCATCAGAAAAAAGAAGCACATAATGCTTTTG GTGCGATGGCACTCACTGTGAACATGTGTAACCACATATTAATATGCAATATTGTTTCCA ATACTTTCTAATACAGTTTTTTATAATGTTGTGTGTGGTGATTGTTCAGGTCGAATCTGT TGTATCCAGTACAGCTTTAGGTCTTCAGCTGCCCTTCTGGCGAGTACATGCACAGGATTG TAAATGAGAAATGCAGTCATATTTCCAGTCTGCCTCTATGATGATGTTAAATTATTGCTG TTTAGCTGTGAACAAGGGATGTACCACTGGAGGAATAGAGTATCCTTTTGTACACATTTT GAAATGCTTCTTCTGTAGTGATAGAACAAATAAATGCAACGAATACTCTGTCTGCCCTAT CCCGTGAAGTCCACACTGGCGTAAGAGAAGGCCCAGCAGAGCAGGAATCTGCCTAGACTT TCTCCCAATGAGATCCCAATATGAGAGGGAGAAGAGATGGGCCTCAGGACAGCTGCAATA CCACTTGGGAACACATGTGGTGTCTTGATGTGGCCAGCGCAGCAGTTCAGCACAACGTAC CTCCCATCTACAACAGTGCTGGACGTGGGAATTCTAAGTCCCAGTCTTGAGGGTGGGTGG AGATGGAGGGCAACAAGAGATACATTTCCAGTTCTCCACTGCAGCATGCTTCAGTCATTC TGTGAGTGGCCGGGCCCAGGGCCCTCACAATTTCACTACCTTGTCTTTTACATAGTCATA AGAATTATCCTCAACATAGCCTTTTGACGCTGTAAATCTTGAGTATTCATTTACCCTTTT CTGATCTCCTGGAAACAGCTGCCTGCCTGCATTGCACTTCTCTTCCCGAGGAGTGGGGTA AATTTAAAAGTCAAGTTATAGTTTGGATGTTAGTATAGAATTTTGAAATTGGGAATTAAA AATCAGGACTGGGGACTGGGAGACCAAAAATTTCTGATCCCATTTCTGATGGATGTGTCA CACCTTTTCTGTCAAAATAAAATGTCTTGGAGGTTATGA |
Protein Sequence | >10320 : length: 563 MEGAILTSAVSRWEGRETRDNLRTMDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPED LSTTSGGQQSSKSDRVVVTYGADDFRDFHAIIPKSFSPSNVKVETQSDEENGRACEMNGE ECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHK RSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHS VGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVIKEETNHSEMAEDLCKI GSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYEKENEMMKSHVMDQAIN NAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLL SKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYD LLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCG YHSQDRYEFSSHITRGEHRFHMS |